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Researcher Interviews

YAMANAKA Shinya
Director Emeritus / Professor, Center for iPS Cell Research and Application, Kyoto University
Biography
• Born in 1962. Earned a Ph.D. in Medicine from Osaka City University.
Research Theme
Elucidating the Biological Functions of the Gene NAT1 (eIF4G2), Which is Universally Present in Animal Cells and Believed to Be Involved in Protein Translation
• Born in 1962. Earned a Ph.D. in Medicine from Osaka City University.
• JSPS Research Fellow, JSPS Research Fellowship for Young Scientists (1996)
• Assistant Professor, Osaka City University, Medical School (1996)
• Associate Professor, Nara Institute of Science and Technology, Center for Genetic Education and Research (1999)
• Professor, Institute for Frontier Medical Sciences, Kyoto University (2004)
• Director/Professor, Center for iPS Cell Research and Application, Kyoto University (2010)
• Assumed current position in 2022
• Recipient of JSPS Prize (2006)
• Nobel Prize in Physiology or Medicine (2012)
• Assistant Professor, Osaka City University, Medical School (1996)
• Associate Professor, Nara Institute of Science and Technology, Center for Genetic Education and Research (1999)
• Professor, Institute for Frontier Medical Sciences, Kyoto University (2004)
• Director/Professor, Center for iPS Cell Research and Application, Kyoto University (2010)
• Assumed current position in 2022
• Recipient of JSPS Prize (2006)
• Nobel Prize in Physiology or Medicine (2012)
Research Theme
Elucidating the Biological Functions of the Gene NAT1 (eIF4G2), Which is Universally Present in Animal Cells and Believed to Be Involved in Protein Translation

“The support I’ve received from JSPS has been fundamental in allowing me to continue pursuing basic research that delves into the mysteries of life.”
From the early stages of my research career, I received support in various forms, allowing me to advance my research. In 1996, I was selected as a JSPS Postdoctoral Fellow (PD) just after returning from the United States, enabling me to start my research in Japan smoothly. Ten years later, in 2006, I was awarded the JSPS Prize, which was of great encouragement to me in advancing my research further. The support I’ve received from JSPS has been fundamental in allowing me to continue pursuing basic research that delves into the mysteries of life.

“During the course of this research, I became interested in ES cells, which eventually led to developing iPS cells.”
In 1997, my research project titled "Elucidation of the Function of the Translation Inhibitor NAT1 in Vivo and Its Intracellular Signaling Pathway" was selected for a Grant-in-Aid for Scientific Research (KAKENHI) for the first time. This study aimed to clarify the properties of NAT1, a gene I identified as a candidate for tumor suppression. During the course of this research, I became interested in embryonic stem (ES) cells, which eventually led to developing induced pluripotent stem (iPS) cells. This experience demonstrates the pivotal role that KAKENHI grants can play in advancing basic research.

Human iPS cells ©Kyoto University. YAMANAKA Shinya

“The true joy of basic research lies in gradually uncovering the veil of nature’s hidden truths.”
When pursuing basic research, experimental results often do not turn out as expected. People who, instead of feeling discouraged by unexpected results, can feel from them an excitement for the possibility of new discoveries are well-suited for a career in basic research. The true joy of basic research lies in gradually uncovering the veil of nature’s hidden truths. I encourage you to find a field that fascinates you and immerse yourself in it wholeheartedly.
*Profile information accurate as of the time of the interview.
[ Special Content along the JSPS Brochure: Researcher Interviews ]
Be sure to check out more interviews with the other researchers as well!
Dr. YAMANAKA Shinya - Recipient of Grant-in-Aid for Scientific Research (KAKENHI) | Dr. SUGIYAMA Masafumi - Awardee of JSPS Research Fellowships for Young Scientists | Dr. MUKAI Hiromi - Recipient of the "JSPS Ikushi Prize" | Dr. SUGIMURA Miki -Senior Program Officer, Research Center for Science Systems
Be sure to check out more interviews with the other researchers as well!
Dr. YAMANAKA Shinya - Recipient of Grant-in-Aid for Scientific Research (KAKENHI) | Dr. SUGIYAMA Masafumi - Awardee of JSPS Research Fellowships for Young Scientists | Dr. MUKAI Hiromi - Recipient of the "JSPS Ikushi Prize" | Dr. SUGIMURA Miki -Senior Program Officer, Research Center for Science Systems
JSPS Brochure
The brochure containing the Researcher Interviews is available at the following link.
・JSPS Brochure 2024-2025 (PDF/6.3MB)
The brochure containing the Researcher Interviews is available at the following link.
・JSPS Brochure 2024-2025 (PDF/6.3MB)
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