Summary of Research Project Results under JSPS FY2001
"Research for the Future Program"

1.Research Institution Hokkaido University
2.Research Area Life Sciences
3.Research Field Higher Brain Functions
4.Term of Project FY 1997 〜 FY 2001
5.Project Number 97L00205
6.Title of Project Studies on the Brain Functions by Optical Imaging and Magnetoencepharography

7.Project Leader
Name Institution,Department Title of Position
Mamoru,Tamura Hokkaido University, Research Institute for Electronic Science   Professor

8.Core Members

Names Institution,Department Title of Position
Ryusuke, Kakigi Okazaki National Reseach Institute, National Institute for Physiological Sciences Professor
Toru, Yamamoto Hokkaido University, College of Medical Technology Professor
Yoko, Hoshi Tokyo Institute of Psychiatry Head

9.Summary of Research Results

(Hokkaido Univ.)
We developed the new optical techniques of near-infrared computed tomography for brain function. This technique has a unique advantages, such as easy handling, low cost, qutantitative detection of brain function. Our optical CT revealed the presence of working memory when subjects performed the backword digit span. The quantitation of the performance with different subjects is now possible. Combined use of fMRI and fNIRS can give the more information concerning the brain activation.

(National Institute for Physiological Sciences)
We investigated higher brain function in humans, particularly focusing on language and face perception, using magnetoencephalography (MEG). MEG theoretically has a very high time (temporal) resolution in msec, and high spatial resolution in mm. As for language study, we focused on the hearing ability of "L" and "R", which is lacking in Japanese peaple. After training, 70 % of subjects showed a significant increase in the correct rate of differentiating "L" and R". In these people, a function was changed in the auditory cortex in the right temporal lobe, which is considered to play a major role in language study. As for face perception, we found that the inferior temporal lobe and lateral temporal lobe play an important role in the perception of static faces and eye movements, respectively. The right hemisphere is more dominant than the left for the perception of both static faces and eye movement.

10.Key Words

(1)Optical Brain Monitoring(Hokkaido Univ.)、(2)Near-infrared(Hokkaido Univ.)、(3)Optical tomography(Hokkaido Univ.)
(4)fNIRS(Hokkaido Univ.)、(5)Magnetoencephalography(National Institute for Physiological Sciences)、(6)Higher brain function(National Institute for Physiological Sciences)
(7)Language perception(National Institute for Physiological Sciences)、(8)Face perception(National Institute for Physiological Sciences)