| 1.Research Institution | Kyoto University | |
| 2.Research Area | Integrated Fields | |
| 3.Research Field | Tissue Engineering | |
| 4.Term of Project | FY1996〜FY2000 | |
| 5.Project Number | 96I00203 | |
| 6.Title of Project | Tissue engineering for soft tissues |
| Name | Institution,Department | Title of Position |
| Yasuhiko Shimizu | Kyoto University, Institute for Frontier Medical Sciences | Professor |
8.Core Members
| Names | Institution,Department | Title of Position |
| Tatsuo Nakamura | Kyoto University, Institute for Frontier Medical Sciences | Assistant Professor |
| Naohide Tomita | Kyoto University, Institute for Frontier Medical Sciences | Assistant Professor |
| Katsuaki Endo | Kyoto University, Graduate School of Medicine | Assistant |
9.Cooperating Researchers
| Names | Institution,Department | Title of Position |
| Chizuka Ide | Kyoto University, Graduate School of Medicine | Professor |
| Saburo Kawaguchi | Kyoto University, Graduate School of Medicine | Professor |
| Yasuhiko Tabata | Kyoto University, Institute for Frontier Medical Sciences | Professor |
10.Summary of Research Results
|
Our research objective is the regeneration of damaged tissues and organs using a new in situ tissue engineering approach. This method aims to achieve autologous tissue and organ regeneration, and is comprised of the steps of: ・ implantation of a 3-dimentional scaffold made of reconstituted collagen and bioabsorbable synthetic polymer, ・ addition of a DDS consisting of cell growth factors, and ・ when necessary, seeding autologous precursor cells or interesitial stem cells taken from autologous bone marrow. Results: (1) membranous tissues (eg. dura matter), (2) blood vessels, (3) the trachea, (4) the esophagus, (5) permanent teeth and periodontal tissue, (6) bone, (7) and segments of peripheral nerves upto 8cm in length have been successfully regenerated without the need for cell seeding. Successful regeneration has also been achieved in (8) the stomach, intestine, heart, and bladder, but cell seeding was required for full regeneration of proper muscle components. Partial connection of the (9) spinal cord has been achieved without cell seeding, and thus experimentation is continuing to investigate autologous neuron implantation. In (10) the lung, regenerated small bronchi were observed to appear. In (11) the liver, a regenerated, healthy liver structure with new ductal tubes and blood vessels was observed. |
11.Key Words
(1)autologous tissue regeneration、(2)collagen、(3)biodegradable synthetic material
(4)dimensional structure scaffold、(5)cell growth factor、(6)DDS
(7)autologous stem cell、(8)precursor cell
12.References
| Author | Title of Article | |||
| Tetsuya Kiyotani | Nerve regeneration across a 25-mm gap bridged by a polyglycolic acid collagen tube: a histological and electrophysiological evaluation of regenerated nerves. | |||
| Journal | Volume | Year | Pages Concerned | |
| Brain Research | 740(1,2) | 1996 | 66-74 | |
| Author | Title of Article | |||
| Y. Tabata | Biodegradable gelatin micospheres for drug delivery to macrophages. "Microparticulate Systems form the Drug Delivery of Protein and Vaccines" C. Cohen and H. Bernstein Eds | |||
| Journal | Volume | Year | Pages Concerned | |
| Marcel Dekker Inc., New York, | 1996 | 401-423 | ||
| Author | Title of Article | |||
| Y. Otani | A New Biological Glue form Gelatin and Poly (L-glutamic acid) | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomed. Mater. Res., | 31 | 1996 | 157-166 | |
| Author | Title of Article | |||
| Y. Otani | Adhesion to Soft Tissues by Gelatin- Polyanion Hydrogels. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Adhesion | 59 | 1996 | 197-205 | |
| Author | Title of Article | |||
| Y. Otani | Rapidly Curable Biological Glue Composed of Gelatin and Poly (L-Glutamic acid) | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials | 17(14) | 1996 | 1387-1391 | |
| Author | Title of Article | |||
| R. Nakaoka | Antibody Production by Administration of Biodegradable Granules Incorporating Antigen through Different Injection Routes. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Controlled Release | 40 | 1996 | 11-21 | |
| Author | Title of Article | |||
| Kato | Ultrastructure of The Interface Between Cultured Osteoblasts and Polymer Substrates Carrying Organophosphate Graft Chains. | |||
| Journal | Volume | Year | Pages Concerned | |
| Bioceramics | 9 | 1996 | 383-386 | |
| Author | Title of Article | |||
| R. Nakaoka | Production of Interleukin 1 from Macrophages Incubated with Poly (DL-lactic Acid) Granules Containing Ovalbumin. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials | 17 | 1996 | 2253-2258 | |
| Author | Title of Article | |||
| R. Nakaoka | Size Effect on the Antibody Production Induced Biodegradable Microspheres Containing Antigen. | |||
| Journal | Volume | Year | Pages Concerned | |
| Vaccine | 14(13) | 1996 | 1251-1256 | |
| Author | Title of Article | |||
| Y. Murakami | Effect of the molecular weight water-soluble polymers on accumulation at inflammatory site following intravenous injection. | |||
| Journal | Volume | Year | Pages Concerned | |
| Drug Delivery | 3 | 1996 | 231-238 | |
| Author | Title of Article | |||
| R. Nakaoka | Adjuvant effect of biodegradable poly (DL-lactic acid) granules capable for antigen release following intraperitoneal injection. | |||
| Journal | Volume | Year | Pages Concerned | |
| Vaccine | 14 | 1996 | 1671-1676 | |
| Author | Title of Article | |||
| Y. Tabata | Size effect on systemic and mucosal immune responses induced by oral administration of biodegradable microspheres. | |||
| Journal | Volume | Year | Pages Concerned | |
| Vaccine | 14 | 1996 | 1677-1685 | |
| Author | Title of Article | |||
| K. Xu | Liver targeting of interferon thorough pullulan conjugation. | |||
| Journal | Volume | Year | Pages Concerned | |
| Pharmaceutical Research | 13(12) | 1996 | 1846-1850 | |
| Author | Title of Article | |||
| H. Akiyama | 1, 25-Dihydroxyvitamin D3 Inhibits Cell Growth and Chondrogenesis of a Clonal Mouse EC Cell Line, ATDC5 | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Bone and Mineral Research | 11 | 1996 | 22-28 | |
| Author | Title of Article | |||
| Yong- Shun- Chang | Bone remodeling around implanted ceramics | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Biomedical Materials Research | 30 | 1996 | 117-124 | |
| Author | Title of Article | |||
| Kitsugi. T | Bone-bonding behavior of plasma-sprayed coatings of BioglassR, AW-glass ceramic, and tricalcium phosphate on titanium alloy | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Biomedical Materials Research | 30 | 1996 | 261-269 | |
| Author | Title of Article | |||
| Akiyama. H | 1α, 25-Dihydroxyvitamin D3 Inhibits Cell Growth and Chondrogenesis of a Clonal Mouse EC Cell Line, ATDC5 | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Bone And Mineral Research | 11;1 | 1996 | 22-28 | |
| Author | Title of Article | |||
| Yong- Shun- Chang | Significance of interstitial bone ingrowth under load-bearing conditions : a comparison between solid and porous implant materials | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterisals | 17 | 1996 | 1141-1148 | |
| Author | Title of Article | |||
| T. Kitsugi | Bone bonding behavior of titanium and its alloys when coated with titanium oxide (Tio2) and titanium silicate(Ti5Si3) | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Biomedical Materials Research | 32 | 1996 | 149-156 | |
| Author | Title of Article | |||
| M. Takahashi | Enhancement of Bone Bonding to Bioactive Ceramics by basic Fibrobalast Growth Factor | |||
| Journal | Volume | Year | Pages Concerned | |
| Bioceramics | 9 | 1996 | 107-110 | |
| Author | Title of Article | |||
| T. Nakayama | Fracture Healing is a Process Independent of p53 Function | |||
| Journal | Volume | Year | Pages Concerned | |
| in vivo | 10 | 1996 | 553-558 | |
| Author | Title of Article | |||
| K. Shimizu | Correction of Kyphotic Deformity of the Cervical Spine in Ankylosing Spondylitis Using general Anesthesia and Internal Fixation | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Spinal Disorders | 9;6 | 1996 | 540-543 | |
| Author | Title of Article | |||
| T. Tsuboyama | Intra-operative radiation therapy for osteosarcoma | |||
| Journal | Volume | Year | Pages Concerned | |
| XXX WORLD CONGRESS OF THE INTERNATIONAL COLLEGE OF SURGEONS | 1996 | 1069-1072 | ||
| Author | Title of Article | |||
| Shibuya Y | α N Catenin expression in the normal and regenerating chick sciatic nerve. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Neurocytol. | 25 | 1996 | 615-624 | |
| Author | Title of Article | |||
| Ide C. | Peripheral nerve regeneration. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci. Res., | 25 | 1996 | 101-121 | |
| Author | Title of Article | |||
| Igarashi M. | Growth cone collapse and inhibition of neurite growth by botulinum neurotoxin C1:A t-SNARE in axonal growth. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Cell. Biol. | 134 | 1996 | 205-215 | |
| Author | Title of Article | |||
| Shinohara H. | Distribution of microtubular network in postischemic liver dysfunction: its functional and morphological changes. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biochim. Biophys. Acta., | 1317 | 1996 | 27-35 | |
| Author | Title of Article | |||
| Akagi S. | Localization of synapsin in normal fibers and regenerating axonal sprouts of the rat sciatic nerve | |||
| Journal | Volume | Year | Pages Concerned | |
| Histochem. Cell. Biol. | 105 | 1996 | 365-373 | |
| Author | Title of Article | |||
| Minako Ohashi | An observation on subsurface defects of ultra high molecular weight polyethylene due to rolling contact | |||
| Journal | Volume | Year | Pages Concerned | |
| Bio-Medical Materials and Engineering | 6 | 1996 | 441-451 | |
| Author | Title of Article | |||
| Ohashi, N. | A study of Fatigue on Ultra High Molecular Weight Polyethylene for Artificial Joints. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Far East. | 2 | 1996 | 67-68 | |
| Author | Title of Article | |||
| Kamei, N. | In vivo Histological Evaluation of Organophosphate Immobilized Ploymers. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Far East | 2 | 1996 | 115-116 | |
| Author | Title of Article | |||
| Yan, N. | Effects of Static Magnetic Field on the Femur of Normal Rat. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Far East | 2 | 1996 | 173-174 | |
| Author | Title of Article | |||
| K. Ikeuchi | Locomotion of Medical Micro Robot with Spiral Ribs Using Mucus | |||
| Journal | Volume | Year | Pages Concerned | |
| Micro Machine and Human Science'96 | 1996 | 217-222 | ||
| Author | Title of Article | |||
| Ikeuchi, M. | Friction control with a graft layer of a thermo-sensing polymer. | |||
| Journal | Volume | Year | Pages Concerned | |
| Wear | 199 | 1996 | 197-201 | |
| Author | Title of Article | |||
| Masayoshi Teramachi | Intrathoracic Tracheal Reconstruction with a Collagen-Conjug ated Prosthesis: Evaluation of the Efficacy of Omental Wrapping. | |||
| Journal | Volume | Year | Pages Concerned | |
| The Journal of Thoracic and Cardiovascular Surgery | 113(4) | 1997 | 701-711 | |
| Author | Title of Article | |||
| Masayoshi Teramachi | Porous-Type Tracheal Prosthesis Sealed With Collagen Sponge. | |||
| Journal | Volume | Year | Pages Concerned | |
| Ann Thorac Surg | 64 | 1997 | 965-969 | |
| Author | Title of Article | |||
| Yoshihisa Suzuki | A Novel Wound Dressing With an Antibiotic Delivery System Stimulated by Microbial Infection | |||
| Journal | Volume | Year | Pages Concerned | |
| ASA10 Journal | 43 | 1997 | M854-857 | |
| Author | Title of Article | |||
| Kitahara A. K. | Effects of trehalose on free skin flap storage | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Jpn. Plast. Reconstr. Surg. | 17 | 1997 | 147-51 | |
| Author | Title of Article | |||
| Keisuke Yamada | Development of a dural substitute from synthetic bioabsorbable polymers. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Neurosurgery | 86 | 1997 | 1012-1017 | |
| Author | Title of Article | |||
| Keisuke Yamada | Potentiality of bFGF incorporated in biodegradable hydrogels for skull bone regeneration. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Neurosurgery | 86 | 1997 | 871-875 | |
| Author | Title of Article | |||
| Atsuhiro Nagano | Growth factor release from biodegradable gelatin hydrogels for tissue engineering. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Far- East (III) Xingdong Zhang and Yoshito Ikada eds. | 1997 | 4-5 | ||
| Author | Title of Article | |||
| K. Yamada | Potential efficacy of basic fibroblast growh factor incorporated in biodegradablehydrogels for skull bone regeneration. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Neurosurg., | 85 | 1997 | 871-875 | |
| Author | Title of Article | |||
| H. W. Kang | Preparation of injectable gelatin hydrogels for tissue engineering. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Far- East (III) Xingdong Zhang and Yoshito Ikada eds. | 1997 | 9-12 | ||
| Author | Title of Article | |||
| Md. Muniruzzaman | Polyion complexation of basic fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Far- East (III) Xingdong Zhang and Yoshito Ikada eds. | 1997 | p36-39 | ||
| Author | Title of Article | |||
| Md. Muniruzzaman | Protein interaction with gelatin hydrogels for tissue engineering. | |||
| Journal | Volume | Year | Pages Concerned | |
| Porous Materials for Tissue Engineering, D. -M. Liu and V. Dixit eds., Tran Tech. Publication | 250 | 1997 | 89-96 | |
| Author | Title of Article | |||
| Y. Tabata | Size effect of water-soluble polymers and microgels on tumor accumulation. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Far- East (III) Xingdong Zhang and Yoshito Ikada eds. | 1997 | 212-215 | ||
| Author | Title of Article | |||
| Y. Murakami | Tumor accumulation of poly(ethylene glycol) with different molecular weights after intravenous injection. | |||
| Journal | Volume | Year | Pages Concerned | |
| Drug Delivery | 4 | 1997 | 23-31 | |
| Author | Title of Article | |||
| Y. Tabata | Electric charge influence of dextran derivatives on their tumor accumulation after intravenous injection. | |||
| Journal | Volume | Year | Pages Concerned | |
| Drug Delivery | 4 | 1997 | 213-221 | |
| Author | Title of Article | |||
| R. Nakaoka | Prolongation of the serum half-life period of superoxide dismutase bypoly(ethylene glycol) modification. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Controlled Release | 46 | 1997 | 253-261 | |
| Author | Title of Article | |||
| Y. Tabata | Photodynamic effet of polyethylene glycol-modified fullerene on tumor. | |||
| Journal | Volume | Year | Pages Concerned | |
| Jpn. J. Cancer Res. | 88 | 1997 | 1108-1116 | |
| Author | Title of Article | |||
| T. Nakamura | Prevention of HDP Wear(THA with ceramic femoral head) | |||
| Journal | Volume | Year | Pages Concerned | |
| Japanese Orthopaedic Association | 71(3) | 1997 | S3 | |
| Author | Title of Article | |||
| Y. Matsuda | Femoral component made of Ti-15Mo-5Zr-3Al alloy in total hip arthroplasty | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Orthopaedic Science | 2 | 1997 | 166-170 | |
| Author | Title of Article | |||
| H. Akiyama | Cloning of a Mouse Smoothened cDNA and Expression Pattems of Hedgehog Signalling Molecules during Chondrogenesis and Cartilage Differentiation in Clonal Mouse EC Cells, ATDC5 | |||
| Journal | Volume | Year | Pages Concerned | |
| Biochemical and Biophysical Res. Communications | 235 | 1997 | 142-147 | |
| Author | Title of Article | |||
| H. Fujita | Bioactive Bone Cement Studied In Canine Total Hip Arthroplasty, 2 Years Follow Up Study | |||
| Journal | Volume | Year | Pages Concerned | |
| Bioceramics | 10 | 1997 | 497-500 | |
| Author | Title of Article | |||
| M. Oka | Bone Remodelling Around Implanted Materials Under Load-Bearing Conditions | |||
| Journal | Volume | Year | Pages Concerned | |
| Bioceramics | 10 | 1997 | 147-150 | |
| Author | Title of Article | |||
| Y-S. Chang | Histologic comparison of tibial articular surfaces against rigid materials and artificial articular cartilage | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Biomedical Materials Research | 37 | 1997 | 51-59 | |
| Author | Title of Article | |||
| M. Oka | SyntheticOsteochondral Replacement of the Femoral Articular Surface | |||
| Journal | Volume | Year | Pages Concerned | |
| 79-B | 1997 | 6 | ||
| Author | Title of Article | |||
| T. Nakayama | Establishment of an Osteoblast-Like Cell Line, MMC2, From p53-Deficient Mice | |||
| Journal | Volume | Year | Pages Concerned | |
| Bone | 21;4 | 1997 | 313-319 | |
| Author | Title of Article | |||
| R. Kakinoki | Nerve regenerationj over a 25-mm gap in rat sciatic nerves using tubes containing blood vessels-the possibility for clinical application. | |||
| Journal | Volume | Year | Pages Concerned | |
| International Orthopedics | 21;5 | 1997 | 332-336 | |
| Author | Title of Article | |||
| Yamamoto T. | The rats target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junction in epithelial cells. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Cell Biol. | 139 | 1997 | 1-11 | |
| Author | Title of Article | |||
| Kawano S. | Immunocytochemical distribution of Ca2+ - independent protein kinase C subtypes (δ, ε, ζ) in regenerating axonal growth cones of rat peripheral nerve. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neuroscience. | 81 | 1997 | 263-273 | |
| Author | Title of Article | |||
| Liu X. | Developmental changes in the subcellular localization chick retinal pigment epithelium. | |||
| Journal | Volume | Year | Pages Concerned | |
| Histochem. Cell. Biol | 108 | 1997 | 35-43 | |
| Author | Title of Article | |||
| Kinoshita M. | Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures. | |||
| Journal | Volume | Year | Pages Concerned | |
| Gene Develop. | 11 | 1997 | 1535-1547 | |
| Author | Title of Article | |||
| Sato K. | Remyelination in the rat dorsal funiculus following demyelination by laser irradiation. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci. Res. | 28 | 1997 | 325-335 | |
| Author | Title of Article | |||
| Fujimoto E. | Basic fibroblast growth factor promotes extension of regenerating axons of peripheral nerve. In vitro experiment using a Schwann cell basal lamina tube model.. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Neurocytol. | 26 | 1997 | 511-528 | |
| Author | Title of Article | |||
| Amino K. | Distribution of the plasmalemmal Ca2+-pump and caveolin in the comeal epithelium during the wound healing process. | |||
| Journal | Volume | Year | Pages Concerned | |
| Current Eye Reserch | 16 | 1997 | 1088-1095 | |
| Author | Title of Article | |||
| Chakrabortty S. | Experimental syringomyelia: Late ultrastructural changes of spinal cord tissue and magnetic resonance imaging evaluation. | |||
| Journal | Volume | Year | Pages Concerned | |
| Surg. Neurol | 48 | 1997 | 246-54 | |
| Author | Title of Article | |||
| Suzuki, Y. | A novel wound dressing with antibiotic delivery system stimulated by microbial infection. | |||
| Journal | Volume | Year | Pages Concerned | |
| ASAIO J. | 43 | 1997 | M854-857 | |
| Author | Title of Article | |||
| Shigeru Kamei | Histological andmechanical evaluation for bone bond@ng of polymer surfaces grafted with a phosphate-containing polymers | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomed Mater Res | 37 | 1997 | 384-393 | |
| Author | Title of Article | |||
| Y. S. Zhou | Study on the possibility of silicon nitride-silicon nitride as amaterial for hip prostheses | |||
| Journal | Volume | Year | Pages Concerned | |
| Materials Science and Engineering C5 | 1997 | 125-129 | ||
| Author | Title of Article | |||
| Ikeuchi K. | Low invasive propulsion of medical devices by traction using mucus | |||
| Journal | Volume | Year | Pages Concerned | |
| Wear | 209 | 1997 | 179-183 | |
| Author | Title of Article | |||
| Yong Ho Lee | Mesothelial Cell Regeneration in Purified Human Amnion Membrane Grafts Implanted in Dog Pericardium. | |||
| Journal | Volume | Year | Pages Concerned | |
| Tissue Engineering | 4(2) | 1998 | 131-141 | |
| Author | Title of Article | |||
| Yukinobu Takimoto | The Experimental Replacement of a Cervical Esophageal Segment with an Artificial Prosthesis with the Use of Collagen Matrix and a Silicone Stent. | |||
| Journal | Volume | Year | Pages Concerned | |
| The Journal of Thoracic and Cardiovascular Surgery | 116(1) | 1998 | 98-106 | |
| Author | Title of Article | |||
| Suzuki, Y. | Evaluation of a novel alginate geldressing: Cytotoxicity to fibroblasts in vitro and foreign body reaction inpig skin in vivo. | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Biomedical Materials Research. | 39 | 1998 | 317-322 | |
| Author | Title of Article | |||
| Suzuki, Y. | A new drug delivery system with controlled release of antibiotic only in the presence of infection. | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Biomedical Materials Research. | 42 | 1998 | 112-116 | |
| Author | Title of Article | |||
| Kitahara, A. K. | Evaluation of collagen nerve guide in facial nerve regenaration. | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Artificial Organs. | 1 | 1998 | 22-27 | |
| Author | Title of Article | |||
| Suzuki, Y. | Development of alginate gel dressing. | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Artificial Organs. | 1 | 1998 | 28-32 | |
| Author | Title of Article | |||
| Suzuki, Y. | Antibiotic delivery system stimulated by microbial infection. | |||
| Journal | Volume | Year | Pages Concerned | |
| New Biomedical Materials, Basic and Applied. Amsterdam: IOS Press | 1998 | pp130-134 | ||
| Author | Title of Article | |||
| Katsumi Hayakawa | Effect of steroid pretreatment on contrast media-induced potassium release. | |||
| Journal | Volume | Year | Pages Concerned | |
| Academic Radiology. | 5(1) | 1998 | 99-101 | |
| Author | Title of Article | |||
| Tatsuo Nakamura | Biodegradation and tumorigenicity of implanted plates made from a copolymer of ε-caprolactone and L-lactide in rat. | |||
| Journal | Volume | Year | Pages Concerned | |
| Joumal of Biomedical Material Resarch. | 42 | 1998 | 475-484 | |
| Author | Title of Article | |||
| Yasuhiko Tabata | Bone Regeneration by Basic Fibroblast Growth Factor Complexed with Biodegradable Hydrogels. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials | 19 | 1998 | 807-815 | |
| Author | Title of Article | |||
| Liu. Hong | Comparison of Bone Regeneration in a Rabbit Skull Defect by Recombinant Human BMP-2 incorporated in Biodegradable Hydrogel and in Solution. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci. Polymer Edn. | 9(9) | 1998 | 1001-1014 | |
| Author | Title of Article | |||
| Susumu Miyamoto | Clinical Application of New Bioabsorbable Artificial Dura Mater | |||
| Journal | Volume | Year | Pages Concerned | |
| A Preliminary Report. J. Artif. Organs | 1 | 1998 | 10-14 | |
| Author | Title of Article | |||
| Y. Tabata | Tumor accumulation of poly(vinyl alcohol) of different sizes after intraveous injeciton. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Controlled Release | 50 | 1998 | 123-133 | |
| Author | Title of Article | |||
| M. Nakamura | Potential efficacy of gelatin microspheres as a new adjuvant for oral vaccination. s. t. p. | |||
| Journal | Volume | Year | Pages Concerned | |
| Potential efficacy of gelatin microspheres as a new adjuvant for oral vaccination. s. t. p. | 8(1) | 1998 | 67-73 | |
| Author | Title of Article | |||
| Y. H. Lee | Mesothelial cell regeneration in purified human amnion membrane grafts implanted in dog pericardium. | |||
| Journal | Volume | Year | Pages Concerned | |
| Tissue Engineering | 4(2) | 1998 | 131-141 | |
| Author | Title of Article | |||
| Y. Tabata | Bone regeneration by basic fibroblast growth factor complexed with biodegradablehydrogel. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials | 19 | 1998 | 807-815 | |
| Author | Title of Article | |||
| Y. Tabata | Biodegradable hydrogels for bone regeneration through growth factor release. | |||
| Journal | Volume | Year | Pages Concerned | |
| Pure & Appl. Chem. | 70(6) | 1998 | 1277-1282 | |
| Author | Title of Article | |||
| L. Hong | Comprison of bone regeneration in a rabbit skull defect by recombinant human BMP-2 incorporated in biodegradable hydrogel and in solution. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci., Polym. Ed. | 9(9) | 1998 | 1001-1014 | |
| Author | Title of Article | |||
| M. Yamamoto | Ectopic bone formation induced by biodegradable hydrogels incorporating bone morphogenetic protein. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci., Polym. Ed. | 9(5) | 1998 | 439-458 | |
| Author | Title of Article | |||
| Md. Munirzzaman | Complexation of basic fibroblast growth factor with gelatin. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci., Polym. Ed. | 9(5) | 1998 | 459-473 | |
| Author | Title of Article | |||
| Y. Tabata | In vitro sorption and desorption of basic fibroblast growth factor from biodegradablehydrogels. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials | 19 | 1998 | 1781-1789 | |
| Author | Title of Article | |||
| Y. Tabata | Comparison of release profiles of various growth factors from biodegradable carriers. | |||
| Journal | Volume | Year | Pages Concerned | |
| Mater. Res. Sci., Symp. Proc. | 530 | 1998 | 13-18 | |
| Author | Title of Article | |||
| Y. Tabata | Growth factor release from amylopectin hydrogel based on copper coordination. | |||
| Journal | Volume | Year | Pages Concerned | |
| Controlled Release | 56 | 1998 | 135-148 | |
| Author | Title of Article | |||
| H. Kimura | Cellular response in subretinal neovascularization induced by bFGF-impregnated microspheres. | |||
| Journal | Volume | Year | Pages Concerned | |
| Invest Ophthalmol Vis Sci | 39 | 1998 | 1324-1356 | |
| Author | Title of Article | |||
| Y. Otani | Preparation of rapidly curable hydrogels from gelatin and poly(carboxylic acid) and their adhesio to skin. Macromole. | |||
| Journal | Volume | Year | Pages Concerned | |
| Chem. Phys. | 130 | 1998 | 169-170 | |
| Author | Title of Article | |||
| Y. Otani | Hemostatic capability of rapidly curable glues from gelatin, poly(L-glutamic acid), and carbodiimide. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials | 19 | 1998 | 2091-2098 | |
| Author | Title of Article | |||
| Y. Otani | Effect of additives on gelation and tissue adhesion of gelatin-poly(L-glutamic acid) mixture. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials | 19 | 1998 | 2167-2173 | |
| Author | Title of Article | |||
| Y. Tabata | Protein release from gelatin matrices. | |||
| Journal | Volume | Year | Pages Concerned | |
| Adv. Drug Delivery Reviews | 31 | 1998 | 287-301 | |
| Author | Title of Article | |||
| H. Fujita | Porous A-W glass-ceramic as intramedullary plug | |||
| Journal | Volume | Year | Pages Concerned | |
| Bioceramics | 11 | 1998 | 645-648 | |
| Author | Title of Article | |||
| R. Kakinoki | Nerve regeneration over a 20-mm gap through a nerve conduit containing blood vessels in rats; the influence of interstump distance on nerve regeneration. | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Neurosurgical Sciences | 12;1 | 1998 | 11-21 | |
| Author | Title of Article | |||
| H. Fujita | Porous AW Glass Ceramic as a Femoral Intramedullary Plug. | |||
| Journal | Volume | Year | Pages Concerned | |
| Bioceramics | 11 | 1998 | 645-648 | |
| Author | Title of Article | |||
| Wei-Qi Yan | Bone bonding in bioactive glass ceramics combined with bone matrx gelatin. | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal Of Biomedical Materials Reserch | 42;2 | 1998 | 258-265 | |
| Author | Title of Article | |||
| H. Matsuoka | Osteoclastic resorption of bone-like apatite formed on a plastic disk as an in vitro assay system. | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal Of Biomedical Materials Reserch | 42;2 | 1998 | 278-285 | |
| Author | Title of Article | |||
| H. Kanoe | Amplification of the CDK4 Gene in Sarcomas Tumor Specificity and Relationship with the RB Gene Mutation. | |||
| Journal | Volume | Year | Pages Concerned | |
| ANTICANCER RESEARCH | 18 | 1998 | 2317-2322 | |
| Author | Title of Article | |||
| Ide C. | Long acellular nerve transplants for allogeneic grafting and the effects of basic fibroblast growth factor on the growth of regenerating axons in dogs. | |||
| Journal | Volume | Year | Pages Concerned | |
| Exp. Neurol. | 154 | 1998 | 199-112 | |
| Author | Title of Article | |||
| Senoo E., | Effects of prelesioned peripheral nerve graft on nerve regeneration in the rat spinal cord. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosurgery | 42 | 1998 | 1347-56 | |
| Author | Title of Article | |||
| Kikukawa S. | Regeneration of dorsal column axons after spinal cord injury in young rats. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci. Lett. | 249 | 1998 | 135-8 | |
| Author | Title of Article | |||
| Shirasu M. | Localization of tyrosine-phosphorylated protein in cultured mouse dorsal root ganglion neurons. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Orthopae. Res. | 16 | 1998 | 690-696 | |
| Author | Title of Article | |||
| Suzuki, Y. | Cytotoxicity to fibroblasts in vitro and foreign body reaction in pig skin in vivo. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Biomed Mater Res. | 39 | 1998 | 317-322 | |
| Author | Title of Article | |||
| Suzuki, Y. | A new drug delivery system with controlled release of antibiotic only in the presence of infection. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Biomed Mater Res. | 42 | 1998 | 112-116. | |
| Author | Title of Article | |||
| Kitahara, A. K. | Evaluation of collagen nerve guide in facial nerve regenaration. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Artif Organs. | 1 | 1998 | 22-27 | |
| Author | Title of Article | |||
| Suzuki, Y. | Development of alginate gel dressing. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Artif Organs. | 1 | 1998 | 28-32 | |
| Author | Title of Article | |||
| Inoue T | Spontaneous regeneration of the pyramidal tract after transection in young rats | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci Lett. | 247 | 1998 | 151-154 | |
| Author | Title of Article | |||
| Kikukawa S | Regeneration of dorsal column axons after spinal cord injury in young rats | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci Lett | 249 | 1998 | 135-138 | |
| Author | Title of Article | |||
| Ito J | Spontaneous regeneration and recovery of hearing function of the central auditory pathway in young rats. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci. Lett. | 254 | 1998 | 173-6 | |
| Author | Title of Article | |||
| Ito J | Regeneration of the lateral vestibulospinal tract in adult rats by transplants of embryonic brain tissue. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci. Lett. | 259 | 1998 | 67-70 | |
| Author | Title of Article | |||
| Ito J | Regeneration of the auditory pathway in adult rats by transplants of fetal brain tissue. | |||
| Journal | Volume | Year | Pages Concerned | |
| NeuroReport | 9 | 1998 | 3815-3817 | |
| Author | Title of Article | |||
| Asada Y | Neural repair of the injured spinal cord by grafting: comparison between peripheral nerve segments and embryonic homologous structures as a conduit of CNS axons. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci. Res. | 31 | 1998 | 241-249 | |
| Author | Title of Article | |||
| ITO J | Axonal regeneration with functional restoration in the vestibulospinal tract in young rats. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci. Res. | 32 | 1998 | 149-156 | |
| Author | Title of Article | |||
| Munehisa Koizumi | Detection of cracks in polyethylene components of retrieved knee joint prostheses | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Orthopaedic Science | 3 | 1998 | 330-335 | |
| Author | Title of Article | |||
| Munehisa Koizumi | Detection of cracks in polyethylene components of retrieved knee joint prostheses | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Orthopaedic Science | Vol.3,Issue6 | 1998 | 330-335 | |
| Author | Title of Article | |||
| Q. C. Yan | Effects of static magnetic field on bone formation of rat femurs | |||
| Journal | Volume | Year | Pages Concerned | |
| Medical Engineering & Physics | 20 | 1998 | 397-402 | |
| Author | Title of Article | |||
| Ikeuchi K. | A new method for accurate measurementof displacement of the knee menisci | |||
| Journal | Volume | Year | Pages Concerned | |
| Proc. Instn. Mech., Engrs. | vol.212 PartH | 1998 | 183-188 | |
| Author | Title of Article | |||
| Kiyoshi Yoshinaka | Experimental study of hydrodynamic propulsion of a medical device with a spiral ribbed impelle | |||
| Journal | Volume | Year | Pages Concerned | |
| Wear | 220 | 1998 | 141-144 | |
| Author | Title of Article | |||
| Koichi KATO | Collagen immobilization onto the surface of artificial hair for improving the tissue adhesion | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Adhesion Science&Technology | 1998 | |||
| Author | Title of Article | |||
| T. Nemoto | Automatic Control of Pressure Support Mechanical Ventilation Using Fuzzy Logic. | |||
| Journal | Volume | Year | Pages Concerned | |
| Am J Crit Care Med | 160(8) | 1999 | 550-556 | |
| Author | Title of Article | |||
| A. K. Kitahara | Facial Nerve Repair Using a Collagen Conduit in Cats. | |||
| Journal | Volume | Year | Pages Concerned | |
| Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery | 33 | 1999 | 187-193 | |
| Author | Title of Article | |||
| T. Tsuda | Prevention of Postoperative Air Leakage from Lungs Using a Purified Human Collagen Membrane-Polyglycolic Acid Sheet. | |||
| Journal | Volume | Year | Pages Concerned | |
| Annals of Thoracic Surgery | 68 | 1999 | 339-342 | |
| Author | Title of Article | |||
| K. Matsumoto | A Novel Surgical Material Made from Collagen with High Mechanical Strength-A collagen Sandwich Membrane. | |||
| Journal | Volume | Year | Pages Concerned | |
| ASAIO Jouranl | 45(4) | 1999 | 288-292 | |
| Author | Title of Article | |||
| Y. Yamamoto | Experimental replacement of the thoracic esophagus with a bioabsorbable artificial collagen silicone composite tube. | |||
| Journal | Volume | Year | Pages Concerned | |
| ASAIO Journal | 45 | 1999 | 311-316 | |
| Author | Title of Article | |||
| T. Sekine | Replacement of the tracheobronchial bifurcation by a newly developed Y-shaped artificial trachea. | |||
| Journal | Volume | Year | Pages Concerned | |
| ASAIO Journal | 45(3) | 1999 | 131-134 | |
| Author | Title of Article | |||
| Y. Suzuki | In Vivo Evaluation of a Novel Alginate Dressing. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Biomed Mater Res | 48 | 1999 | 522-527 | |
| Author | Title of Article | |||
| Yasuhiko Tabata | Skull bone regeneration in primates in response to basic fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Neurosurgery | 91 | 1999 | 851-856 | |
| Author | Title of Article | |||
| Y. Tabata | Neovascularization through biodegradable gelatin microspheres incorporating basic fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci. Polym. Edn. | 10(1) | 1999 | 79-94 | |
| Author | Title of Article | |||
| Y. Tabata | Simple mixing of interferon with a polysaccharide having high liver affinity enables interferon to target to the liver. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Interferon and Cytokine Research | 19 | 1999 | 287-292 | |
| Author | Title of Article | |||
| Y. Otani | Sealing effect of rapidly curable gelatin-poly(L-glutamic acid) hydrogel glue on lung air leak. | |||
| Journal | Volume | Year | Pages Concerned | |
| Ann. Thorac. Surg. | 67 | 1999 | 922-926 | |
| Author | Title of Article | |||
| Y. Tabata | Targeting of tumor necrosis factor to tumor by use of dextran and metal coordination. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Controlled Release | 59 | 1999 | 187-196 | |
| Author | Title of Article | |||
| Y. Tabata | Biodegradation of hydrogel carrier incorporating fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| Tissue Engineering | 5(2) | 1999 | 127-138 | |
| Author | Title of Article | |||
| K. Andriano | In vitro and in vivo comparison of bulk and surface hydrolysis in absorbable polymer scaffolds for tissue engineering. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomed. Mater. 1 Res., Appl. Biomater. | 48 | 1999 | 602-612 | |
| Author | Title of Article | |||
| D. V. Ramesh | Bioabsorbabale microspheres for local drug release in the articulus. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Bioact. Compat. Polym. | 14 | 1999 | 137-149 | |
| Author | Title of Article | |||
| H. W. Kang | Fabrication of porous gelatin scaffolds for tissue engineering | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials | 20 | 1999 | 1339-1344 | |
| Author | Title of Article | |||
| Y. Tabata | Vascularization effect of basic fibroblast growth factor released from gelatin hydrogels with different biodegradabilities. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials | 20 | 1999 | 2169-2175 | |
| Author | Title of Article | |||
| Y. Tabata | Skull bone regeneration in primates in response to basic fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Neurosurg. | 91 | 1999 | 851-856 | |
| Author | Title of Article | |||
| Y. Tabata | Vascularization into a porous sponge by sustained release of basic fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci., Polymer Edn. | 10(9) | 1999 | 957-968 | |
| Author | Title of Article | |||
| M. Yamamoto | Growth factor release from geratin hydrogel for tissue engineering. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Bioact. Compt. Polym. | 14(6) | 1999 | 474-489 | |
| Author | Title of Article | |||
| Y. Tabata | Chemical conjugation of interferon with pullulan and its antiviral activity. s. t. p. | |||
| Journal | Volume | Year | Pages Concerned | |
| Pharma Sciences | 9 | 1999 | 17-21 | |
| Author | Title of Article | |||
| H. Miyamoto | Effect of Focal X-ray Irradiation on Experimental Choroidal Neovascularization. | |||
| Journal | Volume | Year | Pages Concerned | |
| Investigative Ophthalmology & Visual Science | 40(7) | 1999 | 1496-1502 | |
| Author | Title of Article | |||
| Y. Tabata | Surfactant-free preparation of bidegradable hydrogel microspheres for protein release. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Bioactive Compatible Polymers | 14 | 1999 | 371-384 | |
| Author | Title of Article | |||
| T. Yasukawa | Targeted delivery of anti-angiogenic agent TNP-470 using waters-soluble polymer in the treatment of choroidal neovasuclarization. | |||
| Journal | Volume | Year | Pages Concerned | |
| Investigative Ophthalmology & Visual Science | 40(11) | 1999 | 2690-2696 | |
| Author | Title of Article | |||
| M. Nishide | Fate of biodegradable D, L-lactic acid oligomer microspheres in the articulus. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Bioactive Compatible Polymers | 14 | 1999 | 385-398 | |
| Author | Title of Article | |||
| N. Mligiliche | Nerve regeneration through biodegradable gelatin conduits in mice. | |||
| Journal | Volume | Year | Pages Concerned | |
| East African Medical Journal | 76 | 1999 | 400-406 | |
| Author | Title of Article | |||
| Y. Tabata | Vascularization into a porous sponge by sustained release of basic fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci., Polym. Ed. | 10(9) | 1999 | 957-968 | |
| Author | Title of Article | |||
| H. Miyamoto | Suppression of experimental corneal angiogenesis by focal x-ray irradiation. | |||
| Journal | Volume | Year | Pages Concerned | |
| Current Eye Research | 19(1) | 1999 | 53-58 | |
| Author | Title of Article | |||
| T. Fujisato | Crosslinking of amniotic membranes. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci. Polymer Edn | 10(11) | 1999 | 1171-1181 | |
| Author | Title of Article | |||
| M. Oka | Methods to reduce the wear of ultrahigh-molecular-weight polyethylene. | |||
| Journal | Volume | Year | Pages Concerned | |
| Joint Arthroplasty | 109-118 | 1999 | 109-118 | |
| Author | Title of Article | |||
| H, Kanoe | Characteristics of genomic breakpoints in TLS-CHOP translocations in liposarcomas suggest the involvement of Translin and topoisomerase In the process of translocation. | |||
| Journal | Volume | Year | Pages Concerned | |
| Oncogene | 18 | 1999 | 721-729 | |
| Author | Title of Article | |||
| H Fujita | Pressurization of Bioctive Bone Cement In Vitro | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Biomaterials Research. Applied Biomaterials | 48-1 | 1999 | 43-51 | |
| Author | Title of Article | |||
| H. Fujita | Pressurization of Bioactive Bone Cement In Vivo | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomed Mater Res | 48 | 1999 | 43-51 | |
| Author | Title of Article | |||
| H. Akiyama | BBR C;Indian Hedgehog in the Late-Phase Differentiation in Mouse Chondrogenic EC Cells, ATDC5:Upregulation of TypeX Collagen and Osteoprotegein Ligand mRNAs | |||
| Journal | Volume | Year | Pages Concerned | |
| BBRC | 257 | 1999 | 814-820 | |
| Author | Title of Article | |||
| S. Yura | Development of artificial interverteral disk using polyvinyl alcohol hydrogels. | |||
| Journal | Volume | Year | Pages Concerned | |
| SIROT | 1999 | 371-376 | ||
| Author | Title of Article | |||
| H. Sugita | Anisotropy of Osteoporotic Cancellous Bone | |||
| Journal | Volume | Year | Pages Concerned | |
| Bone | 54-5 | 1999 | 513-516 | |
| Author | Title of Article | |||
| M. Oka | CHANGES OF JOINT SURFACES OPPOSING AGAINST VARIOUS BIOMATERIALS | |||
| Journal | Volume | Year | Pages Concerned | |
| Bioceramics | 12 | 1999 | 91-94 | |
| Author | Title of Article | |||
| H. Akiyama | Clonig of a novel gene specially expressed in clonal mouse chondroprogenitor-like EC cells, ATDC5 | |||
| Journal | Volume | Year | Pages Concerned | |
| BBA | 1444 | 1999 | 291-294 | |
| Author | Title of Article | |||
| H. Fujita | Femoral bone resorption observed in canine THA usuing bioactive bone cement. | |||
| Journal | Volume | Year | Pages Concerned | |
| Bioceramics | 12 | 1999 | 517-520 | |
| Author | Title of Article | |||
| H. Akiyama | Molecular Cloning and Biological Activity of a Novel Ha-Ras Suppressor Gene Predominantly Expressed in Skeletal Muscle, Heart, Brain, and Bone Marrow by Differential Display using Clonal Mouse EC Cells, ATDC 5. | |||
| Journal | Volume | Year | Pages Concerned | |
| The Journal of Biological Chemistry | 274;45 | 1999 | 32192-32197 | |
| Author | Title of Article | |||
| Kitada M. | Comparison of the axonal and glial reactions between the caudal and rostral border in the cryoinjured dorsal funiculus of the rat spinal cord. | |||
| Journal | Volume | Year | Pages Concerned | |
| Res. Neural. Neurosci. | 14 | 1999 | 251-263 | |
| Author | Title of Article | |||
| Morihara T., | Distribution of synaptosomal associated protein 25 in nerve growth cones and reduction of neurite outgrowth by botulinum neurotoxin A without altering growth cone morphology on dorsal root ganglion neurons. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neuroscience. | 91 | 1999 | 695-706 | |
| Author | Title of Article | |||
| Suzuki, Y. | Peripheral nerve regeneration across 50 mm gap repaired with a novel nerve guide composed of freeze-dried alginate gel. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci Lett. | 259 | 1999 | 75-78 | |
| Author | Title of Article | |||
| Suzuki, K. | Regeneration of transected spinal cord in young adult rats using freeze-dried alginate gal. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neuroreport. | 10 | 1999 | 2891-2894 | |
| Author | Title of Article | |||
| Ito J | Regeneration of the central auditory pathway in adult rats. | |||
| Journal | Volume | Year | Pages Concerned | |
| Acta Otolaryngol. | 119 | 1999 | 132-134 | |
| Author | Title of Article | |||
| Ito J | Regeneration of the mammalian central vestibular pathway using the rat as animal model. | |||
| Journal | Volume | Year | Pages Concerned | |
| Eur. Arch . Otorhinolaryngol. | 256 | 1999 | 442-444 | |
| Author | Title of Article | |||
| Ito J | Regeneration of the lateral vestibulospinal tract in adult rats by transplants of embryonic brain tissue. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci. Lett. | 259 | 1999 | 67-70 | |
| Author | Title of Article | |||
| Shinichi Todo | Effect of sliding locus on subsurface crack formation in ultra-high-molecular-weight polyethylene knee component | |||
| Journal | Volume | Year | Pages Concerned | |
| Bio-medical Materials and Engineering | 9 | 1999 | 13-20 | |
| Author | Title of Article | |||
| Naohide Tomita | ARTICULATING SHAPE DESIGNING FOR ARTIFICIAL KNEE JOINT | |||
| Journal | Volume | Year | Pages Concerned | |
| Bioceramics | Vol.12 | 1999 | 601-604 | |
| Author | Title of Article | |||
| Yoshizumi Hasegawa | Marrow Cell Culture on Poly-L-Lactic Acid Fabrics Clinical | |||
| Journal | Volume | Year | Pages Concerned | |
| Orthopaedics and Related Research | 358 | 1999 | 235-243 | |
| Author | Title of Article | |||
| Naohide Tomita | Design Concept of Artificial Knee Joint for High Durability Joint | |||
| Journal | Volume | Year | Pages Concerned | |
| Arthroplasty, Springer-Verlag | 1999 | 337-344 | ||
| Author | Title of Article | |||
| Tomita N. | Prevention of fatigue cracks in hip and knee polyethylene components by addition of vitamin E | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of Biomedical Research | 48 | 1999 | 474-478 | |
| Author | Title of Article | |||
| Kang Y | Trans-synaptically induced bursts in regular spiking non-pyramidal cells in deep layers of the ca motor cortex. | |||
| Journal | Volume | Year | Pages Concerned | |
| Cerebral Cortex | 9 | 1999 | 77-89 | |
| Author | Title of Article | |||
| K. Hayakawa | Role of hemolysis in potassium release by iodinated contrast medium. | |||
| Journal | Volume | Year | Pages Concerned | |
| European Radiology | 9 | 1999 | 1357-1361 | |
| Author | Title of Article | |||
| Y. Yamamoto | Intrathoracic esophageal replacement in the dog with the use of an artificial esophagus compose of a collagen sponge with a double-layered silicone tube. | |||
| Journal | Volume | Year | Pages Concerned | |
| Joumal of Thoracic Cardiovascular Surgery | 118 | 1999 | 276-286 | |
| Author | Title of Article | |||
| Y. Liu | A new tracheal bioartificial organ: Evaluation of a tracheal allograft with minimal antigenicity after treatment by detergent. | |||
| Journal | Volume | Year | Pages Concerned | |
| ASAIO Journal | 46(5) | 2000 | 536-539 | |
| Author | Title of Article | |||
| T. Sekine | Collagen coated Y-shaped prosthesis for carinal replacement promotes regeneration of the tracheal epithelium. | |||
| Journal | Volume | Year | Pages Concerned | |
| ASAIO Journal | 46(4) | 2000 | 421-425 | |
| Author | Title of Article | |||
| K. Matsumoto | Use of a newly developed artificial nerve conduit to assist peripheral nerve regeneration across a long gap in dogs. | |||
| Journal | Volume | Year | Pages Concerned | |
| ASAIO Journal | 46(4) | 2000 | 415-420 | |
| Author | Title of Article | |||
| Y. Liu | New type of tracheal bioartificial organ treated with detergent: Maintaining cartilage viability is necessary for successful immunosuppressant-free allotransplantation. | |||
| Journal | Volume | Year | Pages Concerned | |
| ASAIO Journal | 46(5) | 2000 | 536-9 | |
| Author | Title of Article | |||
| Y. Liu | Immunosuppressant-free allotransplantation of the trachea: The antigenicity of tracheal grafts ca be reduced by removing the epithelium and mixed glands from the graft by detergent treatment. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Thorac Cardiovasc Surg | 120 | 2000 | 108-114 | |
| Author | Title of Article | |||
| A. Iwakura | Basic fibroblast growth factor may improve devascularized sternal healing. | |||
| Journal | Volume | Year | Pages Concerned | |
| The Annals of Thoracic Surgery | 70 | 2000 | 824-828 | |
| Author | Title of Article | |||
| A. Iwakura | Novel method to enhance sternal healing after harvesting bilateral internal thoracic arteries. | |||
| Journal | Volume | Year | Pages Concerned | |
| Circulation | 102 | 2000 | III307-III311 | |
| Author | Title of Article | |||
| A. Iwakura | Pericardial fluid frompatients with unstable angina induces vascular endothelial cell apoptosis. | |||
| Journal | Volume | Year | Pages Concerned | |
| Journal of the American College of Cardiology | 35 | 2000 | 1785-1790 | |
| Author | Title of Article | |||
| K. Fujiwara | Experimental embolization of rabbit renal arteries to compare the effects of poly L-lactic acid microspheres with and without Epirubicin release against intraarterial injection of epirubicin. | |||
| Journal | Volume | Year | Pages Concerned | |
| Cadio Vascular and Interventional Radiology | 23 | 2000 | 218-223 | |
| Author | Title of Article | |||
| T. Sekine | Carinal reconstruction with a Y-shaped collagen-conjugated prosthesis. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Thorac. Cardiovasc. Surg. | 119(6) | 2000 | 1162-1168 | |
| Author | Title of Article | |||
| T. Sekine | Experimental carinal replacement with an Y-shaped collagen-conjugated prosthesis | |||
| Journal | Volume | Year | Pages Concerned | |
| Thorac Caridov Surg | 48(3) | 2000 | 125-129 | |
| Author | Title of Article | |||
| K. Matsumoto | Peripheral nerve regeneration across an 80-mm gap bridged by a polyglycolic acid(PGA)-collage tube filled with laminin-coated collagen fibers:a histological and electrophysiological evaluation of regenerated nerves. | |||
| Journal | Volume | Year | Pages Concerned | |
| Brain Research | 868 | 2000 | 315-328 | |
| Author | Title of Article | |||
| T. Nakamura | Artificial trachea and its long-term follow-up after carinal reconstruction in a dog. | |||
| Journal | Volume | Year | Pages Concerned | |
| International Journal of Artificial Organs | 23(10) | 2000 | 718-724 | |
| Author | Title of Article | |||
| T. Sekine | A new type of surgical adhesive made from porcine collagen and polyglutamic acid. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Biomed Mater Res | 54(2) | 2000 | 305-10 | |
| Author | Title of Article | |||
| A. K. Kitahara | Facial nerve repair accomplished by the interposition of a collagen nerve guide. | |||
| Journal | Volume | Year | Pages Concerned | |
| Nournal of Neurosurgery | 93(1) | 2000 | 113-120 | |
| Author | Title of Article | |||
| Atsushi Iwakura | Basic fibroblast growth may improve devascularized sternal healing. | |||
| Journal | Volume | Year | Pages Concerned | |
| Ann Torac Surg | 70 | 2000 | 824-828 | |
| Author | Title of Article | |||
| Atsushi Iwakura | Novel method to enhance sternal healing after harvesting bilateral internal thoracic arteries with use of basic fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| Circulation | 102(suppl III) | 2000 | 307-311 | |
| Author | Title of Article | |||
| L. Hong | Promoted bone healing at a rabbit skull gap between autologous bone fragment and the surrounding intact bone with biodegradable microspheres containing transforming growth factor-betal | |||
| Journal | Volume | Year | Pages Concerned | |
| Tissue Eng. | 6(4) | 2000 | 331-40 | |
| Author | Title of Article | |||
| Y. Tabata | Bone formation at a rabbit skull defect by autologous bone marrow combined with gelatin microspheres containing TGF-β1 | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci., Polym. Ed. | 11(8) | 2000 | 891-901 | |
| Author | Title of Article | |||
| M. Yamamoto | Bone regeneration by transforming growth factor (1 released from a biodegradable hydrogel | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Controlled Release | 64 | 2000 | 133-142 | |
| Author | Title of Article | |||
| L. Hong | Bone regeneration at rabbit skull defects treated with transforming growth factor-β1 incorporate into hydrogels with different levels of biodegradability | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Neurosurg | 92(2) | 2000 | 315-325 | |
| Author | Title of Article | |||
| Y. Tabata | De novo regeneration of adipose tissue by controlled release of basic fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| Tissue Eng. | 6(3) | 2000 | 279-289 | |
| Author | Title of Article | |||
| L. Hong | Promoted bone healing at a rabbit skull gap between autologous bone fragment and the surrounding intact bone with biodegradable microspheres containing transforming growth factor-betal. | |||
| Journal | Volume | Year | Pages Concerned | |
| Tissue Eng. | 6(4) | 2000 | 331-40 | |
| Author | Title of Article | |||
| Y. Tabata | Controlled release of vascular endothelial growth factor by use of collagen hydrogels. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci. Polym. Ed. | 11(9) | 2000 | 915-930 | |
| Author | Title of Article | |||
| Y. Tabata | Bone formation at a rabbit skull defect by autologous bone marrow combined with gelatin microspheres containing TGF-β1. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci., Polym. Ed. | 11(8) | 2000 | 891-901 | |
| Author | Title of Article | |||
| Y. Tabata | Bone regeneration at rabbit skull defects by biodegradable hydrogels incorporating transforming growth factor β1. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Asian (IV) Xingdong Zhang and Yoshito Ikada Eds. | 2000 | 24-25 | ||
| Author | Title of Article | |||
| Y. Tabata | Vascularization into a porous scaffold through controlled release of basic fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Asian (IV) Xingdong Zhang and Yoshito Ikada Eds. | 2000 | 148-149 | ||
| Author | Title of Article | |||
| M. Yamamoto | Promotion of fibrovascular tissue ingrowth into porous sponges by basic fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Mater. Sci. Mater. in Med. | 11 | 2000 | 213-218 | |
| Author | Title of Article | |||
| M. Yamamoto | Controlled release of growth factors from a biodegradable hydrogel for tissue engineering. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Asian (IV) Xingdong Zhang and Yoshito Ikada Eds. | 2000 | 41-42 | ||
| Author | Title of Article | |||
| A. John | A trial to prepare collagen-hydroxyapatite composite in vitro. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Asian (IV) Xingdong Zhang and Yoshito Ikada Eds. | 2000 | 91-92 | ||
| Author | Title of Article | |||
| K. Kawai | Evaluation of basic fibroblast growth factor-impregnated gelatin microspheres incorporated into an artificial dermis. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in the Asian (IV) Xingdong Zhang and Yoshito Ikada Eds. | 2000 | 146-147 | ||
| Author | Title of Article | |||
| K. Kato | Collagen immobilIzation onto the surface of artificial hair for improving the tissue adhesion. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Adhension Sci. Technol. | 14(5) | 2000 | 635-650 | |
| Author | Title of Article | |||
| M. Yamamoto | Bone regeneration by transforming growth factor (1 released from a biodegradable hydrogel. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Controlled Release | 64 | 2000 | 133-142 | |
| Author | Title of Article | |||
| L. Hong | Bone regeneration at rabbit skull defects treated with transforming growth factor-β1 incorporated into hydrogels with different levels of biodegradability. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Neurosurg. | 92(2) | 2000 | 315-325 | |
| Author | Title of Article | |||
| Y. Tabata | Influence of gelatin complexation on cell proliferation activity and proteolytic resistance of basi fibroblast growth factor. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci. Polym. Ed. | 11(6) | 2000 | 571-582 | |
| Author | Title of Article | |||
| H. Nakase | Development of an oral drug delivery system targeting immune-regulating cells in experimental inflammatory bowel disease: A new therapeutic strategy. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Pharmacol. Exp. Ther. | 292(1) | 2000 | 15-21 | |
| Author | Title of Article | |||
| Y. Ikada | Growth factor release from biodegradable hydrogels to induce neovascularization, in "Handbook of Pharmaceutical Controlled Release Technology" Ed. by Don Wise | |||
| Journal | Volume | Year | Pages Concerned | |
| Marcel Dekker Inc | 2000 | 725-742 | ||
| Author | Title of Article | |||
| Y. Tabata | The importance of drug delivery systems in tissue engineering. | |||
| Journal | Volume | Year | Pages Concerned | |
| Pharmaceutical Science & Technology Today | 3(3) | 2000 | 80-89 | |
| Author | Title of Article | |||
| A. Iwakura | Basic fibroblast growth factor may improve devascularized stemal healing. | |||
| Journal | Volume | Year | Pages Concerned | |
| Ann. Thorac. Surg. | 70 | 2000 | 824-828 | |
| Author | Title of Article | |||
| A. Iwakura | Novel method to enhance stemal healing after harvesting bilateral intemal thoracic arteries. | |||
| Journal | Volume | Year | Pages Concerned | |
| Circulation, | 102 | 2000 | III307-III311 | |
| Author | Title of Article | |||
| K. Kawai | Accelerated tissue regeneration through incorporation of basic fibroblast growth factor-impregnated gelatin microspheres into artificial dermis. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials | 21 | 2000 | 489-499 | |
| Author | Title of Article | |||
| C-F. Yang | Experimental corneal neovascularization by basic fibroblast growth factor impregnated in gelatin hydrogel. | |||
| Journal | Volume | Year | Pages Concerned | |
| Ophthalmic Res. | 32(1) | 2000 | 19-24 | |
| Author | Title of Article | |||
| L. Hong | Synergistic effect of gelatin microspheres incorporating TGF-β1 and a physical carrier for fibrous tissue infiltration on skull bone formation. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater Sci. Polym. Ed. | 11(12) | 2000 | 1357-1369 | |
| Author | Title of Article | |||
| K. Morimoto | Gelatin Microspheres as a Pulmonary Delivery System: Evaluation of Salmon Calcitonin Absorption. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Pharm. Pharmacol | 52 | 2000 | 611-617 | |
| Author | Title of Article | |||
| J. Wang | Positively charged gelatin microsphere as gastric mucoadhesive drug delivery system for eradication of H. pylori. | |||
| Journal | Volume | Year | Pages Concerned | |
| Drug Delivery | 7 | 2000 | 237-243 | |
| Author | Title of Article | |||
| A. Iwakura | Basic fibroblast growth factor may improve devascularized stemal healing. | |||
| Journal | Volume | Year | Pages Concerned | |
| Annals of Thoracic Surgery | 70 | 2000 | 824-828 | |
| Author | Title of Article | |||
| H. Fujita | Evaluation of bioactive bone cement in canine total hip arthroplasty. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomed Mater Res | 49 | 2000 | 273-288 | |
| Author | Title of Article | |||
| M. Oka | Development of artificial articular cartilage | |||
| Journal | Volume | Year | Pages Concerned | |
| Pro Instn Mech Engrs | 214 | 2000 | 59-68 | |
| Author | Title of Article | |||
| A. Shukunami | Requirement of autocrine signaling by bone morphogenetic protein-4 for chondrogenic differentiation of ATDC5 cells. | |||
| Journal | Volume | Year | Pages Concerned | |
| FEBS Letters | 469 | 2000 | 83-87 | |
| Author | Title of Article | |||
| H. Fujita | Porous apatite-wollastonite glass-ceramic as an intramedullary plug. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Bone Joint Surg | 82 | 2000 | 614-618 | |
| Author | Title of Article | |||
| H. Yamamoto | High incidence of SV40-like sequences detection in tumor and peripheral blood cells of Japanese osteosarcoma patients. | |||
| Journal | Volume | Year | Pages Concerned | |
| British Journal of Cancer | 82;10 | 2000 | 1677-1681 | |
| Author | Title of Article | |||
| H. Akiyama | Differential expression of BMP family genes during chondrogenic differentiation of mouse ATDC5 cells. | |||
| Journal | Volume | Year | Pages Concerned | |
| CELL STRUCTURE AND FUNCTION | 25 | 2000 | 195-204 | |
| Author | Title of Article | |||
| M. Ikenaga | Thermosensitive drug delivery system containing Cis-platinum with L-lactide-glycolide copolymers. | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomaterials and Drug Delivery toward New Mellenium | 2000 | 519-529 | ||
| Author | Title of Article | |||
| T. Tsuboyama | Intra-operative radiation therapy for osteosarcoma in the extremities. | |||
| Journal | Volume | Year | Pages Concerned | |
| International Orthopaedic (SICOT); | 24 | 2000 | 202-207 | |
| Author | Title of Article | |||
| H. Fujita | Evaluation of Bioactive Bone Cement in Canine Total Hip Arthroplasty | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomed Mater Res | 49 | 2000 | 273-288 | |
| Author | Title of Article | |||
| T. Hosaka | Translin binds to the sequences adjacent to the breakpoints of the TLS and CHOP genes in liposarcomas with translocation t(12;6) | |||
| Journal | Volume | Year | Pages Concerned | |
| Oncogene | 19 | 2000 | 5821-5825 | |
| Author | Title of Article | |||
| Shirasu M. | VAMP-2 promotes neurite elongation and SNAP-25A increases neurite sprouting in PC12 cells | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci Res. | 37 | 2000 | 265-75 | |
| Author | Title of Article | |||
| Nishida A. | Incorporation and differentiation of neural stem cells transplanted in injured adult rat retina. | |||
| Journal | Volume | Year | Pages Concerned | |
| Invest. Ophthalmol. Vis. Sci. | 41 | 2000 | 4268-4274 | |
| Author | Title of Article | |||
| Asai K. | Distinct aggregation of β- and γ-chains of the high-affinity IgE receptor on cross-linking. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Histochem Cytochem. | 48 | 2000 | 1705-1715 | |
| Author | Title of Article | |||
| Okajima S. | Ultrastructural characteristics and synaptophysin immunohistochemistry of regenerating nerve growth cones following traumatic injury to rat peripheral nerve. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Reconstruct. Microsurg. | 16 | 2000 | 637-642 | |
| Author | Title of Article | |||
| Kataoka K. | Alginate, a bioresorbable material derived from brown seaweed, enhances elongation of amputat axons of spinal cord in infant rats. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomed. Mater. Res. | 54 | 2000 | 373-384 | |
| Author | Title of Article | |||
| Suzuki, K. | Reconstruction of rat peripheral nerve gap without sutures using freeze-dried alginate gel. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Biomed Mater Res. | 49 | 2000 | 528-533 | |
| Author | Title of Article | |||
| Suzuki, Y. | Alginate hydrogel linked with synthetic oligopeptide derived from BMP-2 allows ectopic osteoinduction in vivo. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Biomed Mater Res. | 50 | 2000 | 405-409 | |
| Author | Title of Article | |||
| S. Hiraoka | Fixation strength of polylactic-acid thread in cortical bone | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in Asia ( ･ ) | 2000 | 130-131 | ||
| Author | Title of Article | |||
| R. Ohata | Preparation of osteoporosis-model with high reproducibility | |||
| Journal | Volume | Year | Pages Concerned | |
| Biomedical Materials Research in Asia ( ･ ) | 2000 | 140-141 | ||
| Author | Title of Article | |||
| Y. Mu | Metal ion release from titanium with active oxygen species generated by rat macrophages in vitro | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomed. Mater. Res. | 49 | 2000 | 238-243 | |
| Author | Title of Article | |||
| Ying MU | The mechanism of titanium release from its implant in vitro and/or in vivo | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Jpn. Soc. Biomater. | 18(5) | 2000 | 16-22 | |
| Author | Title of Article | |||
| KOJI HATTORI | Bioabsorbable thread for tight tying of bones | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Orthop. Sci | 5 | 2000 | 57-63 | |
| Author | Title of Article | |||
| Okajima S | Freeze-dried alginate sponge enhanses spinai dord axons to erongate across the gap in rat. | |||
| Journal | Volume | Year | Pages Concerned | |
| Soc Neurosci Abstr | 325 | 2000 | 16 | |
| Author | Title of Article | |||
| Ishizaki H | Role of Rab GDP dissociation inhibitor α in regulating plasticity of hippocampal neurotransmission. | |||
| Journal | Volume | Year | Pages Concerned | |
| PNAS | 97 | 2000 | 11587-11592 | |
| Author | Title of Article | |||
| Endo K | μ-Opioid receptor inhibits N-type Ca2+ channels in the calyx presynaptic terminal of the embryonic chick ciliary ganglion. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Physiol | 524 | 2000 | 769-781 | |
| Author | Title of Article | |||
| Suzuki Y | Spinal cord regeneration through alginate, a polysaccharide from seaweed. | |||
| Journal | Volume | Year | Pages Concerned | |
| European J Neurosci | 12,Supplement11 | 2000 | 287 | |
| Author | Title of Article | |||
| Y. Yamamoto | Intrathoracic esophageal replacement with a collagen sponge silicone double layer tube: Evaluation of omental-pedicle wrapping and prolonged placement of an inner stent | |||
| Journal | Volume | Year | Pages Concerned | |
| ASAIO Journal | 46 | 2000 | 734-739 | |
| Author | Title of Article | |||
| Ide C. | Grafting of choroid plexus ependymal cells promotes the growth of regenerating axons in the dorsal funiculus of rat spinal cord | |||
| Journal | Volume | Year | Pages Concerned | |
| A preliminary report. Exp. Neurol. | 167 | 2001 | 242-251 | |
| Author | Title of Article | |||
| Kataoka, K. | Alginate, a bioresorbable material derived from brown seaweed, enhances elongation of amputated axons of spinal cord in infant rats. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Biomed Mater Res. | 54 | 2001 | 373-384 | |
| Author | Title of Article | |||
| Ide C. | Grafting of choroid plexus ependymal cells promotes the growth of regenerating axons in the dorsal funiculus of rat spinal cord | |||
| Journal | Volume | Year | Pages Concerned | |
| A Preliminary report. Exp. Neurol. | 167 | 2001 | 242-251 | |
| Author | Title of Article | |||
| Kuramoto T. | Attractin/Mahogany/Zitter plays a critical role in myelination of the central nervous system. | |||
| Journal | Volume | Year | Pages Concerned | |
| Proc. Natl. Acad. Sci 98 | 2001 | 559-564 | ||
| Author | Title of Article | |||
| Y. Matsugana | Oral immunization with size-purified microsphere beads as a vehicle selectively indcues systemi tolerance and sensitization. | |||
| Journal | Volume | Year | Pages Concerned | |
| Vaccine | 19 | 2001 | 579-588 | |
| Author | Title of Article | |||
| M. Inoue | Regeneration of junctional epithelium and connective tissue after transplantation of detergent processed allo-teeth the international. | |||
| Journal | Volume | Year | Pages Concerned | |
| International Journal of artificial organs | in press | 2001 | ||
| Author | Title of Article | |||
| L. Hong | Synergistic effect of gelatin microspheres incorporating TGF-b1 and a physical carrier for fibrou tissue infiltratio n on skull bone formation | |||
| Journal | Volume | Year | Pages Concerned | |
| J Biomater Sci. Polym. Ed. | in press | 2001 | ||
| Author | Title of Article | |||
| M. Yamamoto | Controlled release of growth factors based on biodegradation of gelatin hydrogel. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci. Polym. Ed. | in press | 2000 | ||
| Author | Title of Article | |||
| T. Yasukawa | Active drug targeting with immunoconjugates to choroidal Neovascularization. | |||
| Journal | Volume | Year | Pages Concerned | |
| Curr. Eye Res. | in press | 2000 | ||
| Author | Title of Article | |||
| Y. J. Gu | Development of a new method to induce angiogenesis at subcutaneous site of strepotozotocin-induced diabetic rats for islet transplantation. | |||
| Journal | Volume | Year | Pages Concerned | |
| Cell transplantation | in press | 2000 | ||
| Author | Title of Article | |||
| N. Nagata | Evaluation of Insulin Secretion of Isolated Rat Islets Cultured in Extracellilar Matrix. | |||
| Journal | Volume | Year | Pages Concerned | |
| Cell transplantation | in press | 2000 | ||
| Author | Title of Article | |||
| A. N. Balamurugan | Prevascularized Intermuscular Space: A Potential Site for Bioartficial Pancreas Transplantation. | |||
| Journal | Volume | Year | Pages Concerned | |
| Cell transplantation | in press | 2000 | ||
| Author | Title of Article | |||
| M. Yamamoto | Controlled release of growth factors based on biodegradation of gelatin hydrogel. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci., Polym. Ed. | in press | 2000 | ||
| Author | Title of Article | |||
| T. Yasukawa | Monoclonal anti-body-mediated drug targeting to neovascular vessels. | |||
| Journal | Volume | Year | Pages Concerned | |
| Investigative Ophthalmology & Visual Science | in press | 2000 | ||
| Author | Title of Article | |||
| K. Morimoto | Evaluation of gelatin microspheres for nasal and intramuscular administrations of salmon calcitonin. | |||
| Journal | Volume | Year | Pages Concerned | |
| Int. J. Pharm. | in press | 2000 | ||
| Author | Title of Article | |||
| Chakrabortty S | Choroid plexus ependymal cells enhance the neurite outgrowth from dorsal root ganglion neurons in vitro. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Neurocytol. | in press | 2001 | ||
| Author | Title of Article | |||
| Mligiliche N. | Grafting of detergent-denatured skeletal muscles provides effective conduits for extension of regenerating axons in the rat sciatic nerve. | |||
| Journal | Volume | Year | Pages Concerned | |
| Arch. Histol. Cytol. | in press | 2001 | ||
| Author | Title of Article | |||
| Yoshida Y. | Altered expression of occludin and tight junction formation in psoriasis. | |||
| Journal | Volume | Year | Pages Concerned | |
| Arch. Dermatol. Res. | in press | 2001 | ||
| Author | Title of Article | |||
| Wu, S., Suzuki | Sciatic nerve regeneration through alginate with tubulation or non-tubulation repair in cat. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Neurotrauma | in press | 2001 | ||
| Author | Title of Article | |||
| Kawasaki, T. | Spatiotemporal distribution of GAP-43 in the developing rat spinal cord: A histological and quantitative immunofluorescence study. | |||
| Journal | Volume | Year | Pages Concerned | |
| Neurosci. Res. | in press | 2001 | ||
| Author | Title of Article | |||
| Hase, T. | Locomotor Performance of the Rat after Neonatal Repairing of Spinal CordInjuries: Quantitativ Assessment and Electromyographic Study. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Neurotrauma | in press | 2001 | ||
| Author | Title of Article | |||
| J. Wang | Positively charged gelatin microspheres as gastric mucoadhesive drug delivery system for eradication of H. Pylori. gelatin microspheres. | |||
| Journal | Volume | Year | Pages Concerned | |
| J Drug Delivery | in press | 2001 | ||
| Author | Title of Article | |||
| L. Hong | Synergistic effect of gelatin microspheres containing TGF-β1 and a physical barrier for fibrous tissue infiltration on skull bone formation. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomater. Sci., Polym. Ed. | in press | 2001 | ||
| Author | Title of Article | |||
| M. Ozeki | Controlled release of hepatocyte growth factor from gelatin hydrogels based on hydrogel degradation. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Drug Targeting | in press | 2001 | ||
| Author | Title of Article | |||
| Y. Tabata | Recent progress in tissue engineering. | |||
| Journal | Volume | Year | Pages Concerned | |
| Pharmaceutical Science & Technology Today | in press | 2001 | ||
| Author | Title of Article | |||
| A. John | Effect of ultrasound exposure on mouse calvaria 3T3-E1 cells. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomedical Engineering, | in press | 2001 | ||
| Author | Title of Article | |||
| Y. Sakakibara | Fetal cardiomyocytes transplantation improves cardiac function in a rat chronic ischemic cridomyopathy model. | |||
| Journal | Volume | Year | Pages Concerned | |
| Circularation | in press | 2001 | ||
| Author | Title of Article | |||
| A. John | A trial to prepare biodegradable collagen-hydroxyapatite composite for bone repairing. | |||
| Journal | Volume | Year | Pages Concerned | |
| Submitted to J. Biomater. Sci., Polym. Ed. | in press | 2001 | ||
| Author | Title of Article | |||
| T. Yamamoto | Intramyocardial delivery of basic fibroblast growth factor-impregnated gelatin hydrogel microspheres enhance collateral circulation to infarcted canine myocardium. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Am. College Cardiology | in press | 2001 | ||
| Author | Title of Article | |||
| K. Kawai | Development of an artificial dermis preparation capable of silver sulfadiazine release. | |||
| Journal | Volume | Year | Pages Concerned | |
| J. Biomed. Mater. Res. | in press | 2001 | ||
| Author | Title of Article | |||
| Y. Hori | Experimental study on in situ tissue engineering of the stomach by acellular collagen sponge scaffold grafting. | |||
| Journal | Volume | Year | Pages Concerned | |
| ASAIO Journal | in press | 2001 | ||
| Author | Title of Article | |||
| Y. Hori | Experimental study on tissue engineering of the small intestine. | |||
| Journal | Volume | Year | Pages Concerned | |
| International Journal of Artificial Organs | in press | 2001 | ||
| Author | Title of Book | ||
| Yasuhiko Shimizu | Tissue Engineering for Therapeutic Use 2 | ||
| Publisher | Year | Pages | |
| Elsevier Science | 1998 | 119-122 | |
| Author | Title of Book | ||
| Ide C | Peripheral nerve regeneration. Neural Development. | ||
| Publisher | Year | Pages | |
| Springer | 1998 | 501-505 | |
| Author | Title of Book | ||
| Ohnishi H | Wear of Total Hip Prosthesis | ||
| Publisher | Year | Pages | |
| Chapman and Hall | 1998 | ||
| Author | Title of Book | ||
| Kawaguchi S | Neural Development | ||
| Publisher | Year | Pages | |
| Springer | 1999 | 506 | |
| Author | Title of Book | ||
| K. Suzuki | Tissue engineering for therapeutic use 3 | ||
| Publisher | Year | Pages | |
| Elsevier Science | 1999 | 71-76 | |
| Author | Title of Book | ||
| Y. Tabata | Biomaterials and Drug Delivery Toward New Milleniums. | ||
| Publisher | Year | Pages | |
| Han Rim Won Publishing Co. | 2000 | 531-544 | |
| Author | Title of Book | ||
| Kawaguchi S | Tissue Engineering for Therapeutic Use 4 | ||
| Publisher | Year | Pages | |
| Elsevier Science | 2000 | 161-165 | |
| Author | Title of Book | ||
| N, TOMITA | POLYMERIC BIOMATERIALS | ||
| Publisher | Year | Pages | |
| Marcel Dekker | 2001 | ||
| Author | Title of Book | ||
| Y. Tabata | Tissue Engineering and Biodegradable Equevalents | ||
| Publisher | Year | Pages | |
| Marcel Dekker | 2001 | ||