18TH US-JAPAN JOINT STEERING COMMITTEE MEETING
Osaka University Medical School
June 30-July 1, 1995
MINUTES
The 18th Joint US-Japan Steering Committee on Cancer Research met on June 30 and July 1, 1995, at the University of Osaka Medical School in Japan. In attendance were Drs. T. Hamaoka, S. Miwa, M. Ogawa, H. Sugano, T. Sugimura, and Messrs. Oakada and Ohkubo, for Japan; and Drs. M. Friedman, T. Kakefuda, S. Thorgeirsson, and F. Welsch, for the United States. The meeting was called to order at 9:00 a.m. by Drs. Miwa and Welsch. They congratulated those present for the success of the joint workshops and scientist exchange programs.
Dr. Friedman stated that a major change had occurred in the political horizon of the U.S. President Clinton in 1993 had Introduced the concept of reinventing government. That meant cutting some 270,000 employees from the work force while making government more responsive to the people and increasing governments efficiency. In November 1994 a Republican Congress had been elected, with a mandate to balance the U.S. budget. And, shortly, a new NCI Director would be appointed. He or she would not necessarily be interested in past bilateral relationships and will insist on evaluating each and all NCI program(s). Therefore, the Joint Steering Committee should start to address the questions of: What would be lost if the US-Japan cooperative program on cancer research were to be canceled? What are the benefits to each side? How is this program unique? Are workshops necessary? Is the scientist exchange program necessary? Is the NCI-JFCR exchange program necessary?
Dr. Welsch distributed copies of the two documents: l) Establishing a more balanced relationship and increased collaboration between Japan and the U.S. in biomedical and behavioral research, which Dr. P. Schambra, Director of the Fogarty International Center presented to his counterparts under the US-Japan Science and Technology agreement; and 2) a summary of the Bishop-Calabresi report published in the Journal of the National Cancer Institute, vol. 87, no. 12, p. 877, June 21, 1995.
Dr. Hamaoka introduced the heads of the different programs at the Osaka Medical School. He mentioned that there were 18 basic science departments, that the clinical center had seen 2,314 cancer patients during 1994 -- 35 percent of them with gastrointestinal cancers -- and that affiliated to the school was the Osaka Biomedical Research Center -- six departments including Dr. Hamaokas oncogenesis department -- the Institute of Microbiology -- five divisions with three or four departments each -- and the Institute of Molecular and Cell Biology -- with six groups. The heads of major units made presentations of their institutes activities.
Given that the progress report for 1994-95 had been distributed in written form, it was decided to spend little time reviewing the years progress. It was suggested that the US-Japan program emphasize more cancer prevention in the future. More time was spent reviewing the plans for 1995-96 (see Appendix I).
The meeting closed at 5:00 p.m. after remarks by Drs. Sugimura, Miwa, Friedman, and Welsch. The meeting was followed by a working dinner hosted by the JSPS. Discussions between the U.S. and Japan representatives continued July 1.
| Respectfully submitted, Federico Welsch, M.D.,Ph.D. |
FUTURE PLANS
1995-1996
Planned Seminar and Exchange Scientists in the Etiology Program Area:
1. PLANNED SEMINARS
| (1) Helicobactor and Gastric Cancer; Prevention and Treatment Hawaii February 1996 |
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| Organizers: | Dr. Jerry Rice Dr. Daizo Saito |
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| Participants: | US - 7 Japan - 7 |
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2) Stem Cell and Carcinogenesis Hawaii December 1-2, 1995 |
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| Organizers: | Dr. Snorri S. Thorgeirsson Dr. Masae Tatematsu |
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| Participants: | US - 7 Japan - 7 |
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(3) Transgenic Animal and Carcinogenesis Hawaii November 29-30, 1995 |
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| Organizers: | Dr. Frank Gonzalez Dr. Nobuyuki Ito |
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| Participants: | US - 7 Japan - 7 |
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(4) Molecular Targets and their Functions for Virally Induced Proliferation of Cells Hawaii January 24-25, 1996 |
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| Organizers: | Dr. Peter Howley Dr. Mitsuaki Yoshida |
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2. EXCHANGE OF SCIENTISTS
| (1) Dr. Norio Hayashi Osaka University |
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| Dates: | October 31 - November 8, 1995 | |
| Host: | Michael A Gerber, Tulane University | |
(2) Dr. Teruhiko Yoshida National Cancer Research Center |
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| Dates: | August 28 - September 14, 1995 | |
| Host: | Thea Tlsty, University of North Carolina Robert M. Hoffman, University of California |
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(3) Dr. Katsumi Imaida Nagoya City University |
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| Dates: | March 17 - 26, 1996 |
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| Host: | Frank J. Gonzalez, National Cancer Institute Ray Tennant, National Institute of Enviromental Health Sciences |
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Planned Seminar and Exchange Scientists in the Biology and Diagnosis Program Area:
1. SEMINARS
| (1) Molecular Mechanisms of Recognition and Regulation in the Immune System Hawaii February 29- March 1, 1996 |
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| Organizers: | Dr. Dinah S. Singer Dr. Takehiko Sasazuki |
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| Participants: | US - 8 Japan - 7 |
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(2) Regulation of Cell Proliferation and Differentiation Hawaii February 15- 17, 1996 |
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| Organizers: | Dr. Robert N. Eisenman Dr. Tadatsugu Taniguchi |
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| Participants: | US - 10 Japan - 7 |
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(3) Cytokines and Tumor Immunity Bethesda January 8-10, 1996 |
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| Organizers: | Dr. Joost Oppenheim Dr. Hiromi Fujiwara |
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| Participants: | US - 10 Japan - 7 |
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2. EXCHANGE OF SCIENTISTS
| (1) Dr. Takashi Suda Osaka Bioscience Institute |
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| Dates: | July 1995 (2 weeks) | |
| Host: | Dr. Mark M. Davis, Stanford University Dr. Francis V. Chisari, The Scripps Research Institute Dr. Gary G Singer, Harvard Medical School Dr. Phillip L Cohen, University of North California |
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(2) Dr Yasuhiro Minami Kobe University School of Medicine |
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| Dates: | September 20- October 4, 1995 | |
| Host: | Dr. Richarad Klausner, National Institute of Health Dr. John OShea, National Institute of Health |
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(3) Dr Ei-ichi Nakayama Okayama University School of Medicine |
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| Dates: | October 1995 (10 days) | |
| Host: | Dr. Lloyd J. Old, Ludwig Institute Cancer Research | |
Planned Seminar and Exchange Scientists in the Treatment Program Area:
1. SEMINARS
| (1) Genetic Engineering Techniques in Cancer Therapy Nagoya January 1996 |
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| Organizers: | Dr. M. A. Friedman Dr. Ryuzo Ueda Dr. Makoto Ogawa |
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| Participants: | US - 6 Japan - 10 |
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(2) New Drugs and New Hematopoietic Factors Hawaii February 1996 |
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| Organizers: | Dr. M. A. Friedman Dr. Takashi Tsuruo Dr. Makoto Ogawa |
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| Participants: | US - 6 Japan - 7 |
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(3) New Treatment Strategies for Hematologic Tumors California March 1996 |
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| Organizers: | Dr. M. A. Friedman Dr. Hideaki Mizoguchi Dr. Makoto Ogawa |
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2. EXCHANGE Of SCIENTISTS
| (1) Dr. Sabro Sone Tokushima University |
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| Dates: | August 27- September 9, 1995 | |
| Host: | Dr. Isaiah J. Fidler, M. D. Anderson Dr. Lance L. Liotta, National Cancer Institute Dr. Avraham A Raz, Michigan Cancer Center |
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(2) Dr. Nagahiro Saijo National Cancer Reaserch Institute |
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| Dates: | September 2-18, 1995 | |
| Host: | Dr. Bruce Chabner, National Cancer Institute Dr. Merrill Egorin, Maryland Cancer Cneter |
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(3) Dr .Jun Yoshida University of Nagoya |
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| Dates: | March 4-18 1996 |
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| Host: | Dr. Edward H. Oldfieid, National Institute of Neurological Disorder & Stroke Dr. Gary J. Nabel, Howard Hughes Medical Cancer Dr. Mitchell S. Berger, University of Washington |
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Planned Seminar and Exchange Scientists in the Interdisciplinary Program Area:
1. SEMINARS
| (1) Werners Syndrome, Analysis of Carcinogenesis in Adult Progeria Hawaii February 1996 |
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| Organizers: | Dr. George Martin Dr. Makoto Goto |
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| Participants: | US - 6 Japan - 7 |
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(2) Molecular Pathology: Its Contribution to Etiology, Early Detection and Prognosis of Cancer Hawaii February 1996 |
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| Organizers: | Dr. Robert W. Miller Dr. William Nelson Dr. Haruo Sugano |
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| Participants: | US - 6 Japan - 7 |
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2. EXCHANGE OF SCIENTISTS
| (1) Dr. Toshiki Watanabe University of Tokyo |
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| Dates: | August - September 1995 | |
| Host: | Dr. Steven Jacobson, National Institute of Neurological Disorders & Stroke |
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(2) Dr. Yo Kato Japanese Foundation for Cancer Research |
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| Dates: | March 1996 | |
| Host: | Dr. A. K. M. Shamsuddin, University of Maryland Hospital |
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18th JOINT US-JAPAN STEERING COMMITTEE MEETING
Osaka, Japan, June 30-July 1, 1995
AGENDA
| June 30 Friday | ||
| 9: 00 a.m. | Welcoming Remarks | Dr. Miwa Dr. Welsch |
| 9:15-10:45 | Overviews of Osaka University Medical School |
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| 1) General Information | Dr. Toshiyuki Hamaoka | |
| 2) Medical School | ||
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Dr. Taisei | |
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Dr. Morito Monden | |
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Dr. Masayuki Miyasaka | |
| 3) Microbial Research Institute for Microbial Diseases | Dr. Tetsu Akiyama | |
| 4) Institute for Molecular &Cellular Biology | Dr. Yoshito Kondo | |
| 10:45-11:00 a.m. | Coffee Break | |
| 11:00-12:00 a.m. | Annual Report for Etiology Program Area | Dr. Thorgiersson Dr. Sugimura |
| Annual Report for Biology and Diagnosis Program Area | Dr. Hamaoka | |
| 12:05 noon | Lunch | |
| 1:25-2:25 | Annual Report for Treatment Program Area | Dr. Ogawa |
| Annual Report for Interdisciplinary Program Area | Dr. Sugano | |
| 2:25-2:40 p.m. | Coffee Break | |
| 2:40-3:40 p.m. | Program Plans for 1995-1996 | |
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Dr. Thorgiersson Dr. Sigimura |
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Dr. Hamaoka | |
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Dr. Ogawa | |
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Dr. Sugano | |
| 3:40-5:40 p.m. | General Discussion | |
| Closing Remarks | Dr. Welsch Dr. Miwa |
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| 6:00 p.m. | Dinner |
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July 1, Saturday |
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| 9:00 a.m. | Free Discussion | |
| Local tour to Kyoto | ||
PARTICIPANTS
NCI Program Coordinators
Dr. Michael A. Friedman
Associate Director for Cancer Therapy
Evaluation Program
Division of Cancer Treatment
Dr. Snorri Thorgeirsson
Chief, Laboratory of Experimental
Carcinogenesis
Division of Cancer Etiology
JSPS Program Coordinators
Dr. Takashi Sugimura
President Emeritus
National Cancer Center
Dr. Toshiyuki Hamaoka
Dean and Professor
Osaka University School of Medicine
Dr. Makoto Ogawa
Director
Aichi Cancer Center Hospital
Dr. Hamo Sugano
Director Emeritus
Cancer Chemotherapy Center
Japanese Foundation for Cancer Research
NCI Representatives
Dr. Federico Welsch
Associate Director for
Internationl Affairs
Dr. Tsuyoshi Kakefuda
Executive Secretary
for US-Japan Cooperative
Cancer Research Program
JSPS Representatives
Dr. Shiro Miwa
Director
Mr. Kazuhiko Okada
Head
Research Cooperation Division
Mr. Masahiro Ohkubo
Section Head
Research Cooperation Division