ADMINISTRATIVE REPORT
This report summarizes activities of the US-Japan Cooperative Cancer Research Program for the Japanese Fiscal Year 1989, the period between April 1, 1989, and March 31, 1990.
The Program consists of the following program areas:
| I. | Etiology |
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| II. | Biology and Diagnosis |
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| III. | Treatment |
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| IV. | Interdisciplinary | |
The US-Japan Bilateral Agreement calls for the exchange of scientists, the exchange of materials, and the organization of seminars and workshops. Detailed discussions of these activities will be reported under specific program areas. The tables compiled in this section represent overall summaries for quick review. They should be self-explanatory.
To discuss policy matters and program activities, the Joint Steering Committee of the Program meets once every year. The first meeting of the fourth five-year period of its operation (April 1989 to March 1994) was held on June 23-24, 1989, in Kashiko-jima, Japan.
| 1st | 24-25 March 1979 | San Francisco, California |
| 2nd | 10-11 June 1980 | Nara, Japan |
| 3rd | 1-2 June 1981 | Annapolis, Maryland |
| 4th | 31 May-1 June 1982 | Tokyo, Japan |
| 5th | 9-10 June 1983 | Honolulu, Hawaii |
| 6th | 13-14 February 1984 | Tokyo, Japan |
| 7th | 25-26 June 1984 | San Francisco |
| 8th | 27-28 June 1985 | Tokyo, Japan |
| 9th | June 26-27, 1986 | Anchorage, Alaska |
| 10th | June 25-26, 1987 | Kyoto, Japan |
| 11th | June 23-24, 1988 | Anchorage, Alaska |
| 12th | June 23-24, 1989 | Kashiko-jima, Japan |
| 13th | June 28-29, 1990 | San Diego, California |
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Area
|
Seminar & Symposia
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Exchange of Scientists
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Exchange of Materials
|
||
|
from US to Japan
|
from Japan to US
|
from US to Japan
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from Japan to US
|
||
| Etiology |
4
|
0
|
5
|
2
|
1
|
| Biol & Diag. |
3
|
0
|
3
|
0
|
0
|
| Treatment |
3
|
0
|
3
|
0
|
0
|
| Interdisp. |
2
|
0
|
2
|
0
|
0
|
| Total |
12
|
0
|
13
|
2
|
1
|
| (1) Human Cancer Genes; Growth Factor and Tumor-Suppressor Genes Lihue, Hawaii, January 22-24, 1990 |
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| Organizers: | Dr. Stuart Aaronson Dr. Masaaki Terada |
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| Participants: | U.S. - 6 Japan - 8 Canada - 1 |
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| (2) Recent Advances in Research on Heterocyclic Amines Lihue, Hawaii, March 19-22, 1990 |
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| Organizers: | Dr. Snorri Thorgeirsson Dr. Hiroyasu Esumi Dr. Minako Nagao |
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| Participants: | U.S. - 6 Japan - 8 |
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| (3) Multifactorial Etiology and Multistep Development of Hepatocellular Carcinoma Lihue, Hawaii, March 19-22, 1990 |
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| Organizers: | Dr. Dennis Hsieh Dr. Setsuo Hirohashi |
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| Participants: | U.S. - 8 Japan - 8 |
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| (4) Molecular Mechanisms of Tumor Promotion and Progression Osaka, March 28-29, 1990 |
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| Organizers: | Dr. William F. Benedict Dr. Curtis Harris Dr. Hirota Fujiki |
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| Participants: | U.S. - 8 Japan - 11 Europe - 4 |
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| (1) Dr. Minako Nagao National Cancer Center Research Institute | ||
| Dates: | July 8-22, 1989 | |
| Host Scientist(s): | Dr. Herbert S. Rosenkranz, Case Western University Dr. Marvin S. Legator, University of Texas |
|
| (2) Dr. Masashi Shibuya Institute of Medical Science, University of Tokyo | ||
| Dates: | November 26 - December 10, 1989 | |
| Host Scientist(s): | Dr. Hidesaburo Hanafusa, Rockefeller Univ | |
| (3) Dr. Ken-ichi Yamamura Kumamoto University | ||
| Dates: | January 8-21, 1990 | |
| Host Scientist(s): | Dr. Mario R. Capecchi, Univ. of Utah Dr. Francis V. Chisari, Research Inst. of Scripps Clinic |
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| (4). Dr. Osamu Kato National Cancer Ctr. Research Institute | ||
| Dates: | September 23 - October 13, 1989 | |
| Host Scientist(s): | Dr. Peter M. Howley, NCI | |
| (5) Dr. Akio Matsukage Aichi Cancer Center. Research Institute | ||
| Dates: | August 26 - September 5, 1989 | |
| Host Scientist(s): | Dr. Samuel H. Wilson, NCI Dr. Michael Levine, Columbia Univ. Dr. Bruce Stillman, Cold Spring Harbor Lab. |
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From
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To
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| 1. MeIQx 3 gm | Dr. Shozo Takayama | Dr. Richard Adamson |
| 2. 4-8-DiMeIQx 2 gm | Dr. Shozo Takayama | Dr. Richard Adamson |
| 3. Fecapentaene | Dr. Richard Adamson | Dr. Shozo Takayama |
| (1) Lymphocyte Development and Activation Rockville, MD February 19-21, 1990 |
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| Organizers: | Dr. Richard Hodes Dr. Hiromi Fujiwara |
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| Participants: | U.S. - 11 Japan – 8 |
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| (2) Transgenic Mouse Approach to Cancer Research Napa Valley, CA, December 7-8, 1989 |
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| Organizers: | Dr. Stanley J. Korsmeyer Dr. Takehiko Sasazuki |
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| Participants: | U.S. - 9 Japan - 6 |
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| (3) Cell Differentiation and Cancer Kauai Island, Hawaii, January 18-20, 1990 |
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| Organizers: | Dr. Igor B. Dawid Dr. Tasuku Honjo |
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| Participants: | U.S. - 9 Japan - 8 |
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| (1) Dr. Tadashi Utakoji Japanese Foundation for Cancer Research | ||
| Dates: | February 25 - March 18, 1990 | |
| Host Scientist(s): | Dr. Berton Zbar, NCI-Frederick Cancer Research and Development Center Technology Dr. Patrick H. O’Farrell and Dr. Sheldon Wolff University of California at San Francisco Dr. Carrano, Lawrence Livermore National Laboratory |
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| (2) Dr. Hideo Yagita Juntendo University | ||
| Dates: | February 18 - March 9, 1990 | |
| Host Scientist(s): | Dr. Ellis L. Reinherz, Harvard Medical School Dr. Leonard Herzenberg, Stanford University |
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| (3) Dr. Yasuharu Nishimura Kyushu University | ||
| Dates: | November 4-11, 1989 | |
| Host Scientist(s): | Dr. Steven J. Burakoff, Dana-Farber Cancer Institute | |
| (1) Research Directions of New BRM & Cytotoxic Combination Treatments San Francisco, November 13-14, 1989 |
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| Organizers: | Dr. Michael A. Friedman Dr. Makoto Ogawa |
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| Participants: | U.S.- 6 Japan - 7 |
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| (2) Frontiers of Radlotherapy and the Combined Modalities Kyoto, March 16-18, 1990 |
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| Organizers: | Dr. Mitsuyuki Abe Dr. Theodore L. Phillips |
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| Participants: | U.S. - 7 Japan - 26 |
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| (3) New Agents in Early Clinical Trials Hilo, Hawaii, February 19-20, 1990 |
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| Organizers: | Dr. Michael A. Friedman Dr. Makoto Ogawa |
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| Participants: | U.S. - 6 Japan - 7 |
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| (1) Dr. Yutaka Mishima Kobe University | ||
| Dates: | March 6-10, 1990 | |
| Host Scientist(s): | Dr. J. E. Antoine, National Cancer Institute Dr. M. I. Griebenow, Natl. Engineering Lab., Idaho |
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| (2) Dr. Yoichi Hayakawa University of Tokyo | ||
| Dates: | September 16 - October 4, 1989 | |
| Host Scientist(s): | Dr. Matthew Suffness, National Cancer Institute | |
| (3) Dr. Taketo Mukaiyama Japanese Foundation for Cancer Research | ||
| Dates: | March 5-25, 1990 | |
| Host Scientist(s): | Dr. Michael A. Friedman, National Cancer Institute Dr. Karen Antman, Dana-Farber Cancer Institute Dr. W. I. Bensinger, Fred Hutchinson Cancer Research Center Dr. B. Sikic, Stanford University |
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| (1) Genes Controlling Breast Tumor Behavior Osaka, March 26-28, 1990 |
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| Organizers: | Dr. William McGuire Dr. Keishi Matsumoto |
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| Participants: | U.S. - 7 Japan - 11 |
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| (2) Gastrointestinal Cancer; Ethnicity and Some Other High-Risk Groups Honolulu, Hawaii, March 9-10, 1990 |
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| Organizers: | Dr. Robert Miller Dr. Haruo Sugano |
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| Participants: | U.S. - 7 Japan - 8 Canada - 1 |
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| (1) Dr. Suminori Kono Fukuoka Univ. School of Medicine | ||
| Dates: | September 3 - October 1, 1989 | |
| Host Scientist(s): | Dr. Walter Willett, Harvard Sch. of Public Health | |
(2) Dr. Rikuo Machinami University of Tokyo |
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| Dates: | January 13 - February 12, 1990 | |
| Host Scientist(s): | Dr. K. K. Unni, Mayo Clinic Dr. H. C. Harris, National Cancer Institute Dr. J. Rosai, Yale University at New Haven Hospital |
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