AGENDA
DIAGNOSIS AREA SEMINAR ON ONCODEVELOPMENTAL PROTEINS: BASIC BIOLOGY AND CLINICAL ASPECTS
San Diego, California, December 4 and 5, 1980
| Thursday, December 4, 1980 OFFICIAL OPENING |
||
| 8:30- 8:40am | Welcome | W. H. Fishman |
| 8:40- 9:00 | Modification of Oncodevelopmental Gene Expression | W. H. Fishman |
| MODIFICATION WITH ANTI-RFP ANTIBODIES | ||
| Co-Chairpersons: K.R. McIntire, Y. Tsukada | ||
| 9:00- 9:30 | Effect of Anti-AFP Antibody on Tumors and Fetuses | H. Hirai |
| 9:30-10:00 | Purification of AFP and its Antibody | S. Nishi K. Kobayashi H. Hara H. Hirai |
| 10:00-10:30 | Biochemical and Histological Analysis of the Effect of Anti-AFP Antibody on Development of Hepatoma in Rats with DAB | H. Kaneda H. Ishizuka K. Sato Y. Suzuki M. Takahashi H. Taga T. Honda H. Hirai |
| 10:30-10:45 | COFFEE | |
| AFP IN HUMAN PATIENTS (HEPATOMA, CIRRHOSIS, HEPATITIS, TERATOCARCINOMA) | ||
| Co-Chairpersons: I. Arias, T. Oda | ||
| 10:4 5-11:15am | Dynamics of AFP in Patients with Hepatoma and Teratocarcinoma in Surgery |
Y. Kasai J. Uchino |
| 11:15-11:45 | Dynamics of AFP in Patients with Hepatitis, Liver Cirrhosis, and Hepatoma | T. Oda Y. Endo |
| 11:45- 1:00pm | LUNCH | |
| HEPATOMA DIAGNOSIS, RADIOIMMUNODETECTION OF CANCER |
||
| Co-Chairpersons: T. Koji, E. Engvall | ||
| 1:00- 1:45 | Hepatocellular Carcinoma in Man: Epidemiology, Relation to Hepatitis B, and Advances in Diagnosis | I. Arias |
| 1:45- 2:30 | Radioimmunodetection of Cancer | D. M. Goldenberg |
| 2:30- 2:45 | COFFEE | |
| 2:45- 3:15 | Radioimmunodetection of AFP-producing Tumor for Early Diagnosis | T. Koji N. Ishii |
| 3:15-5:00 | Discussion | |
| Friday, December 5, 1980 DIFFERENTIATION AND NEOPLASTIC TRANSFORMATION OF HEPATOCYTES |
||
| Co-Chairpersons: E. Ruoslahti, K. Dempo | ||
| 8:45- 9:15am | Studies on Differentiation of Liver Cells In Vitro | J. Y. Chou |
| 9:15- 9:45 | Demonstration of Oncodevelopmental Proteins in Rat Liver During the Course of DAB Hepatocarcinogenesis | M. Mori K. DeTapo T. Onoe |
| 9:45-10:15 | Early Cellular Events during Chemical Carcinogenesis In Vivo | S. Sell |
| 10:15-10:30 | COFFEE | |
| 10:30-11:00 | Developmental Programs and Procarcinogen Processing in Primary Hepatocyte Cultures | H. Leffert |
| TESTICULAR AND YOLK SAC TUMORS | ||
| Co- Chairpersons: E. Ruoslahti, S. Nishi | ||
| 11:00-11:30am | Testicular Carcinoma and Fetal Proteins | K. R. McIntire |
| 11:30-12:00 | Experimental Yolk Sac Tumor in Rat and Tumor-associated Basic Protein Isolated from the Tumor | Y. Tsukada S. Sakashita H. Hirai |
| 12:00- 1:30pm | LUNCH | |
| ONCOTROPHOBLAST PROTElNS | ||
| Co-Chairpersons: S. Sell, Y. Endo | ||
| 1:30- 2:00 | The Oncoplacental Protein, SP1 | E. S. Engvall |
| 2:00- 2:30 | Trophoblast Gene Modulation | S. Tokumitsu W. H. Fishman |
| 2:30- 2:45 | COFFEE | |
| CONCEPTUAL PERSPECTIVES ON ONCODEVELOPMENTAL PROTEINS | ||
| Co-Chairpersons: W.H. Fishman, H. Hirai |
||
| 2:45- 3:30 | Cell-matrix Interactions in Developmental Biology and Oncology | E. Ruoslahti |
| 3:30- 4:15 | The Present Status of the "Blocked Ontogeny" Hypothesis of Neoplasia | V. R. Potter |
| 4:15- 5:00 | Current Concepts on the Inter-relationships of Embryology and Oncology | D. Solter |
PARTICIPANTS
JAPAN
*Kimimaro Dempo, M.D., Ph.D.
Lecturer, Department of Pathology
Sapporo Medical College
S1, W.17, Chuo-ku
Sapporo 060, Japan
Yasuo Endo, M.D.
Lecturer, The First Department of Internal Medicine
Faculty of Medicine
University of Tokyo
7-3-1 Hongo, Bunkyo-ku
Tokyo 113, Japan
Hidematsu Hirai, M.D., Ph.D.
Professor
Department of Biochemistry
Hokkaido University School of Medicine
Sapporo 060, Japan
*Nobuko Ishii, M.D.
Lecturer, Department of Internal Medicine
Health Service Center of Nagasaki University
1-14 Bunkyo-machi
Nagasaki 852, Japan
*Hideo Ishizuka, M.D.
Instructor, The Third Department of Internal Medicine
Surugadai Hospital
Nihon University School of Medicine
1-8-13 Surugadai, Kanda, Chiyoda-ku
Tokyo 101, Japan
Haruo Kaneda, M.D.
Associate Professor, The Third
Department of Internal Medicine
Surugadai Hospital
Nihon University School of Medicine
1-8-13 Surugadai, Kanda, Chiyoda-ku
Tokyo 101, Japan
Toshihiko Koji, M.D.
Professor, Department of Internal Medicine
Health Service Center of Nagasaki University
1-14 Bunkyo-machi
Nagasaki 852, Japan
Michio Mori, M.D.
Associate Professor
Department of Pathology
Sapporo Medical College
S.1, W.17, Chuo-ku
Sapporo 060, Japan
Shinzo Nishi, M.D., Ph.D.
Associate Professor
Department of Biochemistry
Yamanashi Medical School
Tamaho, Yamanashi 409-38, Japan
*Takashi Okamoto, M.D.
Instructor, The Third Department of Internal Medicine
Surugadai Hospital
Nihon University School of Medicine
1-8-13 Surugadai, Kanda, Chiyoda-ku
Tokyo 101, Japan
*Yuji Suzuki, M.D.
Instructor, The Third Department of Internal Medicine
Surugadai Hospital
Nihon University School of Medicine
1-8-13 Surugadai, Kanda, Chiyoda-ku
Tokyo 101, Japan
*Hiroko Taga, M.D.
Chief Technician, Department of Internal Medicine
Nihon University School of Medicine
1-7-3 Surugadai, Kanda, Chiyoda-ku
Tokyo 101, Japan
*Masaru Takahashi, M.D.
Instructor, The Third Department of Internal Medicine
Surugadai Hospital
Nihon University School of Medicine
1-8-13 Surugadai, Kanda, Chiyoda-ku
Tokyo 101, Japan
*Yutaka Tsukada, M.D., Ph.D.
Associate Professor
Department of Biochemistry
Hokkaido University School of Medicine
Sapporo 060, Japan
Yutaka Yoshida, M.D., Ph.D.
Instructor
Department of Pathology
Sapporo Medical College
S.1, W.17, Chuo-ku
Sapporo 060, Japan
UNITED STATES
lrwin M. Arias, M.D.
Professor of Medicine
Albert Einstein College of Medicine of Yeshiva University
1300 Morris Park Avenue
Bronx, New York 10461
Janice Y. Chou, Ph.D.
Senior Investigator
Pregnancy Research Branch, NICHD
National Institutes of Health
Building 6, Room 128
Bethesda, Maryland 20205
Eva S. Engvall, Ph.D.
Principal Investigator
La Jolla Cancer Research Foundation
2945 Science Park Road
La Jolla, California 92037
William H. Fishman, Ph.D.
President
La Jolla Cancer Research Foundation
2945 Science Park Road
La Jolla, California 92037
David M. Goldenberg, M.D., Ph.D.
Division of Experimental Pathology
University of Kentucky, MS-409
Lexington, Kentucky 40506
*James Hoch, Ph.D.
Department of Cellular Biology
Scripps Clinic and Research Foundation
10666 North Torrey Pines Road
La Jolla, California 92037
*Sally Hoch, Ph.D.
Department of Cellular Biology
Scripps Clinic and Research Foundation
10666 North Torrey Pines Road
La Jolla, California 92037
Barbara Knowles, Ph.D.
Associate Professor
The Wistar Institute
Thirty-Sixth Street at Spruce
Philadelphia, Pennsylvania 19104
Hyam L. Leffert, M.D.
Assistant Professor
Department of Medicine
Division of Pharmacology
University of California, San Diego, M-013
La Jolla, California 92093
K. Robert McIntire, M.D.
Chief, Diagnosis Branch
Division of Cancer Biology and Diagnosis
National Institutes of Health
Bethesda, Maryland 20205
Van Rensselaer Potter, Ph.D.
Hilldale Professor of Oncology
McArdle Laboratory for Cancer Research
University of Wisconsin
Madison, Wisconsin 53706
Erkki Ruoslahti, M.D.
Director of Scientific Affairs
La Jolla Cancer Research Foundation
2945 Science Park Road
La Jolla, California 92037
Stewart Sell, M.D.
Professor, School of Medicine
Department of Pathology
University of California, San Diego, M-012
La Jolla, California 92093
Davor Solter, M.D., Ph.D.
The Wistar Institute
Thirty-Sixth Street at Spruce
Philadelphia, Pennsylvania 19104
Howard H. Sussman, M.D.
Department of Pathology
Stanford University School of Medicine
Stanford, California 94305
Shin-Ichi Tokumitsu, M.D.
Research Associate
La Jolla Cancer Research Foundation
2945 Science Park Road
La Jolla, California 92037
*Terry Wepsic, M.D.
Veterans Administration Hospital
3550 La Jolla Village Drive
San Diego, California 92161
* Observers