AGENDA
SIXTH ANNUAL PROGRAM REVIEW MEETING CANCER TREATMENT PROGRAM AREA U.S.-JAPAN COOPERATIVE CANCER RESEARCH PROGRAM
Tokyo, Japan, June 7 and 8, 1980
| Saturday, June 7, 19800 |
||
| 9:00- 9:10am | Welcome | Yoshio Sakurai |
| OVERVIEW OF FIVE YEARS OF PROGRESS | ||
| Chairman: Dr. Y. Sakurai | ||
| 9:10- 9:30 | Remarks | Stephen Carter |
| PROGRAMMATIC ORGANIZATIONS | ||
| Chairman: Dr. S.K. Carter | ||
| 9:30- 9:50 | The Program of Development of Cancer Chemotherapy in Japan | Yoshio Sakurai |
| 9:50-10:10 | The Cancer Therapy Evaluation Program | Richard Ungerleider |
| 10:10-10:25 | Discussion | |
| 10:25 | COFFEE | |
| RADIATION ONCOLOGY | ||
| Chairmen: Dr. G. Sheline and Dr. T. Sugahara | ||
| 10:40-11:00 | Overview of Progress and Programs to Date | Glenn Sheline |
| 11:00-11:20 | Radiation Sensitizer Studies in Japan | Tsutomu Sugahara |
| 11:20-11:40 | The NCI Radiation Development Program | Glenn Sheline |
| 11:40-12:00 | Discussion | |
| 12:00 | LUNCH | |
| TOPICS IN DRUG DEVELOPMENT (Part I) | ||
| Chairmen: Dr. A. Goldin and Dr. S. Tsukagoshi | ||
| 1:30- 1:50pm | The Current Status of NCI Screening | Abraham Goldin |
| 1:50- 2:10 | Toxicology Screening in Small Animals | William Bradner |
| 2:10- 2:20 | Discussion | |
| TOPICS IN DRUG DEVELOPMENT (Part II) | ||
| Chairmen: Dr. J. Douros and Dr. R. White | ||
| 2:20- 2:40 | Methods of Experimental and Clinical Evaluation of Immune Modulators | Ichiro Azuma |
| 2:40- 3:00 | The Current Status of the NCI Natural Products Branch | John Douros |
| 3:00- 3:10 | Discussion | |
| 3:10 | COFFEE | |
| BIOLOGIC RESPONSE MODIFIERS | ||
| Chairmen: Dr. A. Fefer and Dr. I. Azuma | ||
| 3:25- 3:45 | The NCI Biologic Response Modifier Program | Alexander Fefer |
| 3:45- 4:05 | Interferon, Preclinical Basis for Clinical Trials with Japanese Fibroblast Interferon | Tateshi Kataoka |
| 4:05- 4:25 | Interferon Development in the United States | Richard White |
| 4:25- 4:45 | Problems in Clinical Evaluation | Stephen Carter |
| 4:45- 5:05 | Discussion | |
| THE U.S.-JAPAN COOPERATIVE TRIAL IN GASTRIC CANCER | ||
| Chairman: Dr. S. Carter | ||
| 5:05- 5:25 | Remarks | Makoto Ogawa Michael Friedman |
| 5:25- 5:35 | Discussion | |
| 5:35 | Adjourn | |
| 6:30- 8:30 | COCKTAILS and DINNER | |
| Sunday, June 8, 1980 NEW DRUG TOPICS |
||
| Chairmen: Dr. W. Bradner and Dr. Y. Okami | ||
| 9:00- 9:20am | Bestatin A | |
| Protease Inhibitor: Bestatin | Ikuro Kimura | |
| 9:20-9:30 | Discussion | |
| 9:30-10:10 | Bleomycin | |
| Peplemycin | Hisanobu Niitani (Hiomi Homma) |
|
| Tallysomycin | William Bradner | |
| 10:10-10:25 | Discussion | |
| 10:25 | COFFEE | |
| 10:40-11:40 | Anthracyclines | |
| Chairmen: Dr. J. D. Douros and Dr. M. Ogawa | ||
| Aclacinomycin | Kazumasa Yamada | |
| Anthracyclines under Development in the United States | Stephen Carter | |
| Carminomycin and Marcellomycin | William Bradner | |
| 11:40- 11:55 | Discussion | |
| 11:55 | LUNCH | |
| 1:30- 2:30pm | Nitrosoureas | |
| Chairmen: Dr. M. Friedman and Dr. K. Yamada | ||
| Chlorozotocin | Richard Ungerleider | |
| MCNU and GANU | Makoto Ogawa | |
| PCNU | Michael Friedman | |
| 2:30-2:45 | Discussion | |
| 2:45 | COFFEE | |
| 3:00- 3:40 | Fluoridated Pyrimidines | |
| Chairmen: Dr. R. Ungerleider and Dr. Y. Koyama | ||
| HCFU | Yoshiyuki Koyama | |
| Ftorafur in the United States | Michael Friedman | |
| 3:40-3:55 | Discussion | |
| 3:55- 4:35 | Overview of New Drugs of Interest | |
| Chairman: Dr. W. Bradner | ||
| The United States | Stephen Carter | |
| Japan | Shigeru Tsukagoshi | |
| 4:35-4:45 | Discussion | |
| 4:45 | SUMMARY and CLOSING REMARKS | Stephen Carter |
PARTICIPANTS
JAPAN
Dr. Ichiro Azuma
Professor
Institute of Immunological Sciences
Kita 15-jo Nishi 7-chome
Kita-ku, Sapporo 060
Dr. Tateshi Kataoka
Chief -in-Research
Division of Experimental Chemotherapy
Cancer Chemotherapy Center
Japanese Foundation for Cancer Research
Kami-Ikebukuro 1-37-1
Toshima-ku, Tokyo 170
Dr. Ikuro Kimura
Professor
Department of Internal Medicine II
Okayama University School of Medicine
Shikada-cho 2-5-1
Okayama 700
Dr. Yoshiyuki Koyama
Director, National Medical Center Hospital
Toyama-cho 1
Shinjuku-ku, Tokyo 162
*Dr. Akira Matsuda
Research Director
Department of Anti-cancer and Anti-microbials
Research Laboratories
Nippon Kayaku Company, Ltd.
Shimo 3-31
Kita-ku, Tokyo 115
Dr. Hisanobu Niitani
Chief, Clinical Laboratory
Department of Internal Medicine
National Cancer Center Hospital
Tsukiji 5-1-l
Chuo-ku, Tokyo 104
Dr. Makoto Ogawa
Chief
Division of Clinical Chemotherapy Cancer Chemotherapy Center
Japanese Foundation for Cancer Research
Kami-Ikebukuro 1-37-1
Toshima-ku, Tokyo 170
Dr. Yoshiro Okami
Director, Microbiology
Institute of Microbial Chemistry
Kami-Osaki 3-14-23
Shinagawa-ku, Tokyo 141
Dr. Yoshio Sakurai
Director
Cancer Chemotherapy Center
Japanese Foundation for Cancer Research
Kami-Ikebukuro 1-37-1
Toshima-ku, Tokyo 170
*Dr. Shunichi Oki
Chief, Central Research Laboratory
Sanraku-Ocean Company, Ltd.
Jonan 4-9-1
Fujisawa 251
Dr. Tsutomu Sugahara
Director, Kyoto National Hospital
Professor, Department of Experimental Radiology, Faculty of Medicine
Kyoto University
Yoshida-Konoe-machi
Sakyo-ku, Kyoto 606
*Dr. Tomohisa Takita
Chief of Chemistry
Institute of Microbial Chemistry
Kami-Osaki 3-24-23
Shinagawa-ku, Tokyo 141
Dr. Shigeru Tsukagoshi
Chief, Division of Experimental Chemotherapy
Cancer Chemotherapy Center
Japanese Foundation for Cancer Research
Kami-Ikebukuro 1-37-1
Toshima-ku, Tokyo 170
*Dr. Yoichiro Umegaki
Head, Department of Radiology
Cancer Institute Hospital
Japanese Foundation for Cancer Research
Kami-Ikebukuro 1-37-1
Toshima-ku, Tokyo 170
Dr. Kazumasa Yamada
Associate Professor
First Department of Internal Medicine
Nagoya University School of Medicine
Tsurumai-cho 65
Showa-ku, Nagoya 466
UNITED STATES
Dr. William Bradner
Director
Antitumor Biology Department
Bristol Laboratories
Post Office Box 657
Syracuse, New York 13201
Dr. Stephen K. Carter
Director, Northern California Cancer Program
1801 Page Mill Road
Building B, Suite 200
Palo Alto, California 94304
Dr. John Douros
Chief, Natural Products Branch
Developmental Therapeutics Program
Division of Cancer Treatment
National Cancer Institute
Blair Building, Room 514
8300 Colesville Road
Silver Spring, Maryland 20910
Dr. Alexander Fefer
Professor of Medicine
Head, Division of Oncology
University Hospital
University of Washington
1959 N.E. Pacific Avenue
Seattle, Washington 98105
Dr. Michael Friedman
Assistant Professor of Medicine
Cancer Research Institute
University of California School of Medicine
San Francisco, California 94143
Dr. Abraham Goldin
Assistant Director
International Treatment Research
Division of Cancer Treatment
National Cancer Institute
Building 31, Room 10A-22
National Institutes of Health
Bethesda, Maryland 20205
Dr. Glenn E. Sheline
Professor and Vice Chairman
Department of Radiation Oncology
University of California
San Francisco, California 94143
Dr. Richard S. Ungerleider
Senior Investigator
Clinical Investigations Branch
Cancer Therapy Evaluation Program
Division of Cancer Treatment
National Cancer Institute
Landow Building, Room 8C08
Bethesda, Maryland 20205
Dr. Richard White
Division of Cancer Treatment
National Cancer Institute
Building 37, Room 5D16
Bethesda, Maryland 20205
* Observers