SEMINAR AGENDA AND PARTICIPANTS

1) 1979 U.S.-JAPAN ANNUAL PROGRAM REVIEW: New Drugs under Clinical Evaluation and Their Application in Treatment of Solid Tumors
Sheraton-Palace Hotel, Market & New Montgomery San Francisco (Regency Room), May 21-22, 1979

AGENDA

May 21
8:30 Welcome and Introduction Dr. Stephen K. Carter
I. Anthracyclines (Chairman: Dr. Abraham Goldin )
8:40 Current Status of Studies with AD-32 Dr. Ronald Blum
8:55 Current Status of U.S. Studies with Carminomycin Dr. Robert Comis
9:05 Current Status of Japanese Studies with Aclacinomycin-A Dr. Toshikazu Oki
9:20 Overview of the NCI Anthra-cycline Program Dr. Nicholas Bachur
9:40 An Overview of the Anthra-cycline Cardiac Toxicity Studies Program at Stanford Dr. John Daniels
10:00-10:15 Discussion
10:15-10:30 Coffee Break
II. Bleomycins (Chairman: Dr. Hamao Umezawa)
10:30 Current Status of PEP Bleomycin Studies in Japan Dr. Shigeo Ikeda
10:50 Tallysomycin Studies in the U.S. Dr. Stanley Crooke
11:05 Discussion
III. Fluorinated Pyrimidines (Chairman: Dr. Michael Friedman)
11:20 Status of New Fluorinated Pyrimidine Analogues in Japan Prof. Yoshio Sakurai
11:40 U.S. Studies on the Pharmacology of Ftorafur Dr. Wolfgang Sadee
12:00-12:30 Discussion
12:15-2:15 LUNCH
IV. Nitrosoureas (Chairman: Prof. Yoshio Sakurai)
2:20 Current Status of GANU and Other Nitrosoureas in Japan Dr. Makoto Ogawa
2:40 PCNU Studies in the Northern California Oncology Group Dr. Michael Friedman
2:55 The Experimental Rationale for New Nitrosourea Development Dr. Kurt Kohn
3:15-3:30 Discussion
3:30-3:45 Coffee Break
V. Other New Drugs (Chairman: Dr. Stephen K. Carter)
3:45 New Natural Products in Development Dr. John Douros
4:00 The Current NCI Screening Approach and Its Status Dr. Abraham Goldin
4:20 New Drugs in Phase I Study in the U.S. Dr. Franco Muggia
4:40 Bestatin Studies in Japan Dr. Hamao Umezawa
5:00 A Review of Clinical Studies on Bestatin Dr. Sutemi Oka
5:10 N4-Behenoyl-Cytosine Arabinoside Studies in Japan Dr. Kazumasa Yamada
5:30-5:45 Discussion
6:30 DINNER FOR PARTICIPANTS


May 22
I. Gastric Cancer (Chairman: Dr. Franco Muggia)
8:30 Current Status of U.S. Studies with Chlorozotocin Dr. Philip Schein
9:10 Current Status of FAM Studies Dr. Philip Schein
9:25 Surgical Adjuvant Studies in the U.S. Dr. George Higgins
9:40 The NCOG-Japanese Gastric Cancer Study Dr, Michael Friedman and Dr. Makoto Ogawa
10:10-10:15 Discussion
10:15-10:30 Coffee Break
II. Oat Cell Lung Cancer (Chairman: Dr. Hugh Davis )
10:30 Oat Cell Lung Studies in Japan Dr. Harurnichi Ikegami
10:50 The Development of Non-cross resistant Combinations Dr. Oleg Selawry
11:10 The NCOG Study Comparing POCC vs. VAM Dr. John Daniels
11:30 Combined Modality Studies in the U.S.: An Overview Dr. Robert Livingston
11:55-12:15 Discussion
12:15-2:00 LUNCH
III. Head and Neck Cancer (Chairman: Dr. Makoto Ogawa)
2:00 Combination Chemotherapy of Head and Neck Cancer in U.S. Dr. Robert Wittes
2:20 Platinum plus Methotrexate Dr. Charlotte Jacobs
2:40-3:00 Discussion
3:00-3:15 Coffee Break
IV. Breast Cancer (Chairman: Dr. Philip Schein)
3:30 Current Status of Chemotherapy in Advanced Disease in the U.S. Dr. Hugh Davis
4:00 Current Status of Chemotherapy in Advanced Disease in Japan Dr. Tomio Wada
4:20 Adjuvant Chemotherapy-Where We are Today Dr. Stephen K. Carter
4:45-5:00 Discussion


PARTICIPANTS

United States
Dr. Stephen Carter Northern California Cancer Program P.O. Box 10144 Palo Alto, CA 94303
Dr. Ronald H. Blum Sidney Farber Cancer Institute 44 Binney Street Boston, MA 02115
Dr. Robert Comis Upstate Medical Center 750 East Adams Street Syracuse, NY 13201
Dr. Nicholas R. Bachur Baltimore Cancer Research Center 655 West Baltimore Street Baltimore, MD 21201
Dr. John Daniels Stanford University Medical Center. Room MO11 Stanford, CA 94305
Dr. Stanley Crooke Bristol Laboratories P.O. Box 6575 Syracuse, NY 13201
Dr. Wolfgang Sadee D Room 840-S University of California M San Francisco, CA 94143
Dr. Michael Friedman1276 Moffitt University of California San Francisco, CA 94143
Dr. Charlotte Jacobs Stanford University Me Medical Center, Room C005 Stanford, CA 94305
Dr. Hugh David Wisconsin Clinical Cancer Center 600 Highland Avenue Madison, WI 53792
Dr. Kurt Kohn National Cancer Institute Building 37, Room 5D19 Bethesda, MD 20205
Dr. John Douros National Cancer Institute Blair Building, Room 312 8300 Colesville Road Silver Spring, MD 20910
Dr. Abraham Goldin National Cancer Institute Building 37, Room 6A17 Bethesda, MD 20205
Dr. Franco Muggia National Cancer Institute Building 37, Room 6A17 Bethesda. MD 20205
Dr. Philip Schein Georgetown University Medical Center 3800 Reservoir Road Washington, D.C. 20007
Dr. George Higgins Veterans Admin. Medical Center 50 Irving Street, N.W. Washington, DC 20422
Dr. Oleg Selawry 13720 S.W. 70th Avenue Miami, FL 33158
Dr. Robert Livingston University of Texas Health Sciences Center 703 Floyd Curl Drive an Antonio, TX 78284
Dr. Robert Wittes Memorial Sloan Kettering Cancer Center 275 York Avenue New York, NY 10021

Japan
Yoshio Sakurai, Ph.D. (Coordinator) Director, Cancer Chemotherapy Center Japanese Foundation for Cancer Research Kami-Ikebukuro 1-37-1, Toshima-ku Tokyo 170 Tel.: 03-918-3716
Shigeo Ikeda, M.D., Professor Department of Dermatology Saitama Medical School Moro-hongo 38, Moroyama-machi Iruma-gun, Saitama Pref. 350-04 Tel.: 04929-4-1212
Harumichi Ikegami, M.D., Chief Department of Lung Cancer The Center for Adult Diseases, Osaka Nakamichi 1-3-3, Higashinari-ku Osaka 537 Tel.: 06-972-1181
Tomio Wada, M.D., Chief Department of Surgery, Breast Cancer Service The Center for Adult Diseases Osaka Nakamichi 1-3-3, Higashinari-ku Osaka 537 Tel.: 06-972-1181
Makoto Ogawa, M.D., Chief Division of Clinical Chemotherapy Cancer Chemotherapy Center Japanese Foundation for Cancer Research Kami-Ikebukuro 1-37-1, Toshima-ku Tokyo 170 Tel.: 03-918-0111 Ext. 2668
Sutemi Oka, M.D., Consultant Institute of Microbial Chemistry Kami-Osaki 3-14-23 Shinagawa-ku, Tokyo 141 Tel.: 03-441-4173
Hamao Umezawa, M.D., Director Institute of Microbial Chemistry Kami-Osaki 3-14-23 Shinagawa-ku, Tokyo 141 Tel.: 03-441-4173
Kazumasa Yamada, M.D. Associate Professor The 1st Dept. of Internal Medicine Nagoya University, School of Medicine Tsurumai-cho 65, Showa-ku Nagoya 466 Tel.: 052-741-2111
Toshikazu Oki, Ph.D., Chief Central Research Laboratory Sanraku-Ocean Co., Ltd. Jonan Fujisawa, Kanagawa Pref. 251 Tel.: 0466-34-4176
Akira Matsuda, Ph.D. Research Director Research Laboratories Dept. of Anticancers and Anti-microbials Nippon Kayaku Co., Ltd. Shimo 3-13-12, Kita-ku Tokyo 115



2) Seminar on “High LET and Allied Areas in Radiotherapy”
Kyoto, Japan, May 22-23, 1979

AGENDA

May 22, 1979
8:10 Opening Remarks Glenn E. Sheline, Ph.D., M.D. and Akira Tsuya, M.D.
Radiation Therapy Program Coordinators
I. HIGH LET
A. Accelerator Design (Moderators: M. Goitein & T. Fukumoto)
8:15 Design of heavy ion accelerator for medical use Y. Hirao (Institute for Nuclear Study, Tokyo Univ.)
8:30 Negative-pion production by electrons from thick nuclear targets at immediate energies K. Tsukada (Institute for Nuclear Energy, Nippon Univ.)
8:35 PIGMI-pion generator for medical irradiation E. Knapp (Los Alamos Sci. Lab. Univ. of California)
B. Particle Physics (Moderators: M. Goitein & Y. Hirao)
8:55 Characterization of pion therapy beam at LAMPF A. Smith (Los Alamos Sci. Lab. Univ. of California )
9:15 Radiobiological physics of heavy-ion beams C. Tobias (Donner Lab., Univ. of California, Berkeley)
9:35 Proton field shaping by spot scanning T. Inada (Div. of Clin. Res. Tsukuba Univ.)
9:55 Microdosimetry of high LET therapeutic beam A. Ito (Cyclotron Unit, Inst. of Medical Sci. (IMS), Tokyo Univ.)
10:15 Break for Coffee (15 mins.)
C. Biology (Moderators: T. Phillips & K. Sakamoto )
10:30 Biological basis of high LET radiation therapy K. Sakamoto (Dept, of Rad. Biophys Tokyo Univ.)
10:50 Biological effectiveness of the NIRS cyclotron produced neutron beams for radiotherapy H. Ohara (Div. of Physiol. and Path., Natl. Inst. of Rad. Sci. (NIRS) )
11:10 Update of neutron radiation biology E. Hall (Dept. of Radiol. Columbia Univ.)
11:30 Radiobiology of heavy ions M. Raju (Los Alamos Sci. Lab. Univ. of California)
11:50 LUNCH
1:00 The RBE as a function of fraction size for heavy particles T. Phillips (Dept. of Rad. Oncol., Univ. of California, SF)
1:20 Radiobiology of pions M. Raju (Los Alamos Sci. Lab. Univ. of California)
D. Treatment Planning (Moderators: T. Phillips & T. Inada)
1:40 Treatment planning for pion therapy patient. at LAMPF A. Smith (Cancer Research and Treatment Center, Univ of New Mexico)
2:00 NIRS proton therapy facility K. Kawachi Div. of Physics, Natl. Inst. of Radiol. Sci.
2:20 Treatment planning with proton beams with special emphasis on the use of computed tomography M. Goitein Dept. of Rad. Med. Harvard Med. Sch.
2:40 An update on treatment planning for heavy-ion therapy J. Castro Saroni Tumor Inst. of Mount Zion Hosp. and Lawrence Berkeley Lab. of the Univ. of California, Berkeley
3:00 Break for Coffee (15 mins.)
E. Therapy (Moderators: H. Suit & Y. Umegaki )
3:15 Results of clinical trial with 30 MeV dl-Be neutrons at NIRS H. Tsunemoto Div. of Clin. Res. Natl. Inst. of Radiol. Sci.
3:35 Fast neutron therapy at IMS Y. Iino Dept. of Radiol., IMS, Tokyo Univ.
3:55 Update on clin. neutron trials in the U.S. S. Kramer Dept. of Rad. Therapy & Nucl. Med., Thomas Jefferson Univ. Hosp.
4:15 Fast neutron therapy for squamous cell carcinoma and adenocarcinoma of the uterine cervix S. Morita Div. of Clin. Res. Natl. Inst. of Radiol. Sci.
4:35 Fast neutron therapy for carcinoma of the prostate and urinary bladder Y. Honke Div. of Hosp., Natl. Inst. of Radiol. Sci.
4:55 Adjourn
7:00 to 9:00 RECEPTION AT “CHAGETSU”


May 23, 1979
(Moderators: Y. Umegaki & H. Suit )
8:15 Current status of clinical particle radio-therapy at Lawrence Berkeley Laboratory J. Castro Saroni Tumor Inst. of Mount Zion Hosp. and Lawrence Berkeley Lab. of the Univ. of California, Berkeley
8:35 Current observations of pion radiation therapy at LAMPF M. Kligerman Cancer Res. & Treatment Center, Univ. of New Mexico
8:55 Implementation of fractionated proton radiation therapy at the Harvard Cyclotron Laboratory M. Goitein Dept. of Radiation Medicine, Harvard Medical School
9:15 Clinical evaluation of fractionated proton beam therapy in human cancer patients H. Suit Dept. of Radiation Medicine, Harvard Medical School
II HYPOXIC CELL SENSITIZERS, HYPERTHERMIA AND RADIOPROTECTORS (Moderators: E. Hall and Abe )
1:20 Biological basis of cell sensitizers for radiation therapy T. Sugahara Dept. of Fundamental Radiology, Kyoto Univ.
4:45 Phase I-II clinical studies of the hypoxic cell sensitizer misonidazole in the RTOG T. Phillips Dept. of Radiation Oncology, Univ. of California, SF
10:00 Radiosensitization by misonidazole in animal tumor and prospects of its clinical trial in Japan Y. Onoyama & K. Masuda Dept. of Radiology Kawasaki Med. Col. and Kyushu Univ. Hosp.
10:20 Cytotoxicity of hypoxic cell sensitizers E. Hall Dept. of Radiology Columbia University
Break for Coffee (15 mins.)
11:00 The biological basis Oncology, and clinical potential of sulfhydryl radio-protectors T. Phillips Dept. of Radiation Univ. of California, SF
11:35 Protective effect of WR-2721 K. Tanaka Dept. of Radiology, Tenri Hospital
11:45 Hypoxic cell sensitizer G.E. Adams Inst. for Cancer Research, U.K.
12:00 Hyperthermia and radiation therapy R. Johnson Dept. of Radiation Medicine, Roswell Park Memorial Hosp.
LUNCH
F. High LET Late Damage (Moderators: J. Castro & H. Tsunemoto)
1:40 Complications of particle radiotherapy; the RTOG registry and development of a scoring system S. Kramer Dept. of Radiation Therapy and Nuclear Medicine, Thomas Jefferson Univ. Hosp.
2:00 NIRS Modification of NSD and TDF for the assessment of the figure of merits in radiation therapy Y. Umegaki formerly head of Div. of Clin. Res.
III. INTRAOPERATIVE RADIOTHERAPY (Moderators: J. Castro & M. Abe )
2:20 Intraoperative therapy for malignant disease in Japan M. Abe Dept. of Radiology Kyoto Univ. Hosp.
2:40 Intraoperative electron beam radiation therapy H. Suit Dept. of Radiation Medicine, Harvard Medical School
3:00 Intraoperative therapy for carcinoma of the stomach M. Odaka Dept. of Surgery Chiba Univ. Hosp.
Break for Coffee (15 mins.)
3:30 Clinical experience of intraoperative radiotherapy for pancreatic cancer and brain tumors T. Matsuda Dept. of Radiotherapy Metropolitan Komagome Hospital
3:50 Intraoperative radiotherapy of biliary duct carcinoma K. Todoroki Div. of Clin. Res. Tsukuba Univ.
IV. DIAGNOSTIC APPLICATIONS OF PARTICLES (Moderators: M. Goitein & T. Inada)
4:10 Heavy ion radiography with comments by M. Goitein C. Tobias Lawrence Berkeley Lab. Univ. of California Berkeley
4:35 Closing Remarks
4:45 Adjourn


PARTICIPANTS

United States
G. E. Sheline Univ. of California Professor
A. R. Smith Cancer Res. & Treatment Center Univ. of New Mexico Staff Scientist
C. Tobias Lawrence Berkeley Lab. Professor
E. J. Hall Univ. of Columbia Professor
M. R. Raju LAMP F Staff Scientist
T. L. Phillips Univ. of California Professor
H. D. Suit Harvard Med. Sch. Professor
M. M. Kligerman Univ. of New Mexico Professor
R. T. Johnson Rosewell Park Memorial Inst. Head
S. Kramer Thomas Jefferson Univ. Professor
E. A. Knapp LAMP F Director
M. Goitein Harvard Med. Sch. Staff Scientist
J. R. Castro Univ. of California Professor

(Observers)
E. Blakeley LBL, Staff
S. Curtis LBL, Staff
R. U. Duke Univ. Med. Center Ass. Professor
M. Urano MGH, Ass. Professor

Japan
A. Tsuya, Head Rad. Dep. Cancer Institute Hospital Tokyo
Y. Umegaki, Former Head Division of Clinical Res., NIRS Chiba
T. Inada, Prof. Division of Clinical Res. Tsukuba Univ. Ibaraki
A. Ito, Assistant Cyclotron, IMS, Tokyo, Univ. Tokyo
H. Tsunemoto, Head Division of Clinical Res., NIRS Chiba
Y. Iino, Ass. Prof. Cyclotron, IMS, Tokyo Univ. Tokyo
H. Ohara, Senior Staff Division of Physiology and Pathology NIRS
K. Sakamoto, Ass. Prof. Dept. of Radiation Biophysics Tokyo Univ. Tokyo
M. Abe, Prof. Dept. of Radiology Kyoto Univ. Kyoto
T. Matsuda, Chief Dept. of Radiotherapy Metropolitan Komagome Hosp. Tokyo
T. Sugawara, Prof. Dept. of Fundamental Radiology Kyoto Univ. Kyoto
Y. Onoyama, Prof. Dept. of Radiology Kawasaki Medical College Okayama
Y. Hirao, Prof. Institute for Nuclear Physics Tokyo Univ. Tokyo

(Observers)
S. Morita, Senior Staff Div. of Clinical Research NIRS, Chiba
K. Honke, Senior Staff Div. of Clinical Research NIRS, Chiba
K. Kawachi Senior Staff Div. of Physics NIRS, Chiba
K. Todoroki, Lecturer Div. of Clinical Research Tsukuba Univ. Ibaraki
M. Odaka, Ass. Prof. Dept. of Medicine Chiba Univ. Chiba
K. Tsukada, Prof. Institute for Nuclear Energy Nihon Univ. Tokyo
S. Fukumoto, Prof. KEK, Ibaraki
M. Doyama, Prof. Dept. of Technology Tokyo Univ. Tokyo
K. Masuda, Ass. Prof. Dept. of Medicine Kyushu Univ. Fukuoka
T. Iinuma, Senior Staff Div. of Clinical Research NIRS, Chiba
Y. Nakamura, Senior Staff Div. of Clinical Research NIRS, Chiba
Y. Suda, Senior Staff Div. of Clinical Research NIRS, Chiba
Y. Onai, Head Physics Dept. Cancer Institute, Tokyo
E. Takenaka, Ass. Prof. Dept. of Medicine Tokyo Univ., Tokyo
A. Akanuma, Lecturer Dept. of Medicine Tokyo Univ., Tokyo
M. Akisada, Prof. School of Medicine Tsukuba Univ., Ibaraki
R. Kamata, Ass. Prof. Dept. of Medicine Nihon Univ., Tokyo
T. Kitagawa, Head Rad. Dep. National Cancer Center, Tokyo
M. Takahashi, Ass. Prof. Dept. of Medicine Kyoto Univ., Kyoto
K. Ono Kawasaki Medical College Kurashiki, Okayama
A. Kurisu, Head Hospital Division NIRS, Chiba
T. Nishidai, Assistant Dept. of Medicine Kyoto Univ., Kyoto
K. Tanaka, Head Rad. Dept. Tenri Hospital Tenri, Nara

Third Country
G. E. Adams, Prof. Inst. of Cancer Research U.K.
L. D. Skarsgard, Prof. Brit. Columbia Cancer Research Center Canada



3) JOINT LUNG CANCER SEMINAR
International Hotel, Osaka, January 28-30, 1980

AGENDA
January 28 (Monday)
13:00 Opening Remarks Dr. S. Hattori (Organizer)
Dr. Y. Yamamura (Steering Comm.)
I. INTRODUCTION (Chairman: Dr. Y. Sakurai)
13:10 Multidisciplinary opportunities in the treatment of bronchogenic carcinoma.
(20 min.)
Discussion (10 min.)		 Dr. S. K. Carter
II. EXPERIMENTAL MODELS AND NEW DRUGS
Moderators: Dr. S. K. Carter and Dr. Y. Yamamura
13:40 l. Experimental models for predictive drug effects in lung cancer. (20 min.)
Discussion (10 min.)		 Dr. A. Goldin
14:10 2. Lung metastasis in mice-experimental models and chemotherapy. (20 min.)
Discussion (10 min.)		 Dr. T. Tsuruo
14:40 3. New synthetic immunopotentiating agents and their antitumor activities.(20 min.)
Discussion (10 min.)		 Dr. Y. Yamamura
15:10-15:30 Coffee Break (20 min.)
Moderators: Dr. A. Goldin and Dr. S. Hattori
15:30 4. New drugs of interest and old drugs of renewed-Interest in cancer chemotherapy.(20 min.)
Discussion (10 min.) 		Dr. J. Macdonald
16:00 5. An overview of combination chemotherapy studies in Japan (20 min.)
Discussion (10 min.). 		Dr. M. Ogawa
16:30 6. Combination chemotherapy of metastatic non-small cell lung cancer. (20 min.)
Discussion (10 min.)		 Dr. J. Macdonald
17:00-17:30 Discussion on chemotherapy and experimental models (Modulators: Dr. S. K. Carter and Dr. Y. Sakurai)
17:30 Adjourn
19:00-21:00 Reception (Buffet style) at International Hotel, Osaka All attendants


January 29 (Tuesday)
III. IMMUNOTHERAPY
Moderators: Dr. W. R. Salyer and Dr. Y. Hayata
9:00 1. Non-specific adjuvant immunotherapy of lung cancer with BCG-CWS and Nocardia-CWS.(20 min.)
Discussion (10 min.)		 Dr. K. Yasumoto
9:30 2. Surgical adjuvant immunotherapy of lung cancer (20 min.)
Discussion (10 min.)		 Dr. E. C. Holmes
10:00-10:20 Break (20 min.)
Moderators: Dr. E. C. Holmes and Dr. K. Yasumoto
10:20 3. Experimental lung cancer and its application to clinical model. (20 min.)
Discussion (10 min.)		 Dr. M. Yoshimoto
10:50 4. New developments in immunotherapy-Intralesional BCG. (20 min.)
Discussion (10 min.)		 Dr. E. C. Holmes
11:20-11:50 Discussion on immunotherapy (Modulators: Dr. E. C. Holmes and Dr. K. Yasumoto)
12:00-13:00 Lunch
IV. OAT-CELL CARCINOMA AND MULTIDISCIPLINARY OPPORTUNITY
Moderators: Dr. J. Macdonald and Dr. M. Ogawa
13:10 1. Overview of current oat-cell carcinoma studies in the United States. (20 min.)
Discussion (10 min.)		 Dr. P. Bunn
13:40 2. Combined modality therapy of small cell carcinoma in Japan. (20 min.)
Discussion (10 min.)		 Dr. S. Hattori
14:10 3. A Phase III trial of an alternating VS. A sequential multidrug chemotherapy program for oat-cell cancer-An NCOG study. (20 min.)
Discussion (10 min.)		 Dr. M. Friedmar
14:40-15:00 Coffee Break (20 min.)
Moderators: Dr. H. G. Seydel and Dr. T. Kitagawa
15:00 4. Clinical results of combined radiotherapy and chemotherapy. (20 min.)
Discussion (10 min.)		 Dr. T. Kitagawa
15:30 5. Radiation therapy of oat-cell lung cancer-Current status and new developments. (20 min.)
Discussion (10 min.)		 Dr. H. G. Seydel
Moderators: Dr. M. Friedman and Dr. S. Hattori
16:00 6. Small cell lung carcinoma-Histologic sub-typing. (20 min.)
Discussion (10 min.)		 Dr. W. R. Salyer
16:30 7. Morphologic aspects of cases with small cell carcinoma which survived over 30 months. (20 min.)
Discussion (10 min.)		 Dr. Y. Shimosato
17:00-17:30 Discussion concerning oat-cell lung cancer
(Modulators: Dr. M. Friedman and Dr. S. Hattori)
17:30 Adjourn
19:00-21:00 Dinner at Restaurant Alaska (Invited Speakers)
(Invited Guests)


January 30 (Wednesday)
V. NON-OAT CELL CARCINOMA AND MULTIDISCIPLINARY OPPORTUNITY
Moderators: Dr. P. Bunn and Dr. Y. Shimosato
9:00 Chemotherapy adjuvant trials in resectable disease. (20 min.)
Discussion (10 min.)		 Dr. C. Mountain
9:30 2. Chemotherapy of advanced non-oat cell carcinoma of the lung-In relation to combined therapeutic modalities. (20 min.)
Discussion (10 min.)		 Dr. Y. Hayata
10:00-10:20 Coffee Break
Moderators: Dr. C. Mountain and Dr. Y. Hayata
10:20 3. Current approaches to radiation therapy in non-oat cell lung cancer (20 min.)
Discussion (10 min.) 		Dr. H. G. Seydel
10:50 4. The staging of bronchogenic carcinoma and its impact on clinical trials. (20 min.)
Discussion (10 min.)		 Dr. C. Mountain
11:20-11:50 Discussion concerning non-oat cell lung cancer
(Modulators: Dr. C. Mountain and Dr. Y. Shimosato)
11:50-12:10 SUMMARY AND CLOSING REMARKS Dr. S. K. Carter (Coordinator)
Dr. Y. Sakurai (Coordinator)
12:10-13:00 Lunch
l 3:00 Adjourn
13:00-15:00 BUSINESS MEETING Members of Steering Comm.


PARTICIPANTS

United States
Dr. Stephen K. Carter, Director Northern California Cancer Program 1801 Page Mill Road, Bld. B Suite 200, Palo Alto, CA 94304
Dr. Paul Bunn Veterans Administration Hospital Div. of Oncology 50 Irving St., Washington D.C.
Dr. Michael Friedman 1276 Moffitt Hospital Cancer Research Inst. Univ. of California San Francisco, CA 94143
Dr. Abraham Goldin National Cancer Institute Building 31, Room 10A22 Bethesda, MD 20205
Dr. E. Carmack Holmes Professor of Surgery 54-140 Center for Health Sciences Univ. of California Los Angeles, CA 90024 Dr. Jack Macdonald National Cancer Institute, Building 37, Room 6A17 Bethesda, MD 20205
Dr. Clifton Mountain M.D. Anderson Hospital and Tumor Institute, Univ. of Texas System Cancer Center 6723 Bertner Drive, Houston TX 77025
Dr. William R. Salyer Stanford Univ., Medical Center Room L-223, Stanford, CA 94305
Dr. H. Gunter Seydel Department of Radiation Oncology Wayne State Univ. School of Medicine 3990 John R. Street, Detroit MI 48201

Japan
Dr. Yoshio Sakurai, Director Cancer Chemotherapy Center Japanese Foundation for Cancer Research Kami-Ikebukuro, Toshima-ku Tokyo 170
Dr. Yuichi Yamamura, President Osaka Univ. 33, Joancho, Kita-ku, Osaka 530
Dr. Shoji Hattori, Director Research Institute The Center for Adult Diseases, Osaka Higashinari-ku, Osaka
Dr. Yoshihiro Hayata, Prof. Thoracic Surgery Tokyo Medical College Nishi-shinjuku, Shinjuku-ku Tokyo 160
Dr. Yukio Shimosato, Director Department of Pathology National Cancer Center 5-1, Tsukiji, Chuo-ku, Tokyo 104
Dr. Toshio Kitagawa, Director Department of Radiology National Cancer Center Hospital Tokyo 104
Dr. Makoto Ogawa, Chief Division of Clinical Oncology Cancer Chemotherapy Center Japanese Foundation for Cancer Research Tokyo 170
Dr. Takashi Tsuruo Cancer Chemotherapy Center Japanese Foundation for Cancer Research Tokyo 170
Dr. Kosei Yasumoto, Chief Department of Thoracic Surgery Kyushu Cancer Center 595-Notame, Minami-ku Fukuoka 815
Dr. Munehiko Yoshimoto The Third Department of Internal Medicine Osaka Univ. Fukushima-ku, Osaka 553

Invited Guest
Dr. Shichiro Ishikawa, President National Cancer Center Tokyo
Mr. Barron England

Attendants
Dr. Abe, Prof. Kyoto University Chief, Department of Radiology
Dr. Sawamura, Chief Department of Surgery Kinki Central Hospital, Sakai
Dr. Kimura, Prof. Okayama University Chief, Internal Medicine
Dr. Hirao The Third Department of Internal Medicine Osaka University Medical School
Dr. Ogura The Third Department of Internal Medicine Osaka University Medical School
Dr. Matsuda, Director Department of Lung Cancer The Center for Adult Diseases Osaka
Dr. Doi, Director Department of Thoracic Surgery The Center for Adult Diseases Osaka
Dr. Koyama, Director Department of Breast Cancer The Center for Adult Diseases Osaka
Dr. Ikegami, Chief The Third Department Research Institute The Center for Adult Diseases Osaka
Dr. Tateishi, Chief Department of Pathology Research Institute The Center for Adult Diseases Osaka