SEMINAR AGENDA AND PARTICIPANTS

1) Joint Seminar on “Src and Leuk Genes”
National Institutes of Health, Bethesda, MD, November 12-14, 1979

AGENDA

November 12, 1979
Structure of Endogenous src Protein of CEF Dr. K. Beemon
Studies on the src Proteins of Recovered Avian Sarcoma Viruses Dr. J. Neil
The Nature of Genetic Interaction which Generates Recombinant Sarcoma Virus in Chickens Dr. H. Hanafusa
Unusual Features in the Nucleotide Sequence of a cDNA Clone Derived from the Common Region of Avian Sarcoma Virus Messenger RNA Dr. T. Yamamoto
A New Mutant Derived from ts-NY68 Dr. S. Kawai
Protein Phosphorylation Mediated by the Avian Sarcoma Virus Transforming Gene Product Dr. R. Erikson
Characterization of p60 src Dependent Phosphorylation Products in Cell Free Extracts Dr. G. Jay
Phosphorylation Dr. K. Beemon
The Abelson Murine Leukemia Virus Protein is Phosphorylated in vitro to Form Phosphotyrosite Dr. A. Dasgupta
Protein Phosphorylation in Viral Transformed Cells Dr. Kin-ichiro Oda
Viral-Chemical Carcinogenesis Dr. H. Yoshikura


November 13, 1979
The src Proteins of Rat-Derived Murine Sarcoma Viruses Dr. T. Shih
Presence of Linear ds-DNA in KiSV Producers and Its Mapping Dr. N. Tsuchida
Altered Cytoskeleton in Leukemia Cells Dr. I. Yahara
Ultrastructural Localization of src Proteins Dr. M. Willingham
Identification of SFFV-specific Sequences coding for SFFV-specific Glycoprotein, gp-55 Dr. M. Yoshida
The RNAs of the Detective and Non-Defective Component of Friend Anemia and Polycythemia Virus Identified and Compared: Prototypes of a New Class of Retroviral Transforming Genes Dr. L. Evans
Further Characterization of SFFV-specific gp-55 Dr. Y. Ikawa
Some Properties of a Newly Isolated Avian Sarcoma Virus (Y-73) Dr. K. Toyoshima
Leukemia Specific Sequences in Avian Erythroblastosis Virus Dr. M. Lai


November 14, 1979
The Current Status of Mink Cell Focus Forming Virus Dr. W. Rowe
Malignant Lymphomas Induced by Avian Leukosis Viruses Dr. P. Neiman


PARTICIPANTS

United States

Dr. Paul Neiman
Division of Oncology
University of Washington School of Medicine
Seattle, Washington 98195

Dr. Ira Pastan
Chief, Laboratory of Molecular Biology
National Cancer Institute
National Institutes of Health
Bethesda, Maryland 20205

Dr. Wallace Rowe
Laboratory of Viral Diseases
National Institute of Allergy and Infectious Diseases
National Institutes of Health
Bethesda, Maryland 20205

Dr. Thomas Shih
Laboratory of Tumor Virus Genetics
National Cancer Institute
National Institutes of Health
Bethesda, Maryland 20205

Dr. Mark C. Willingham
Laboratory of Molecular Biology
National Cancer Institute
National Institutes of Health
Bethesda, Maryland 20205

Dr. Tadashi Yamamoto
Laboratory of Molecular Biology
National Cancer Institute
National Institutes of Health
Bethesda, Maryland 20205

Dr. Jim Neil
Department of Microbiology
University of Southern California School of Medicine
2011 Zonal Avenue
Los Angeles, California 90033

Dr. Karen Beemon
Department of Tumor Virology
The Salk Institute
San Diego, California 92112

Dr. Asim Dasgupta
MIT
Center for Cancer Research
77 Massachusetts Avenue
Cambridge, Massachusetts 02139

Dr. Ray Erikson
University of Colorado Medical
School Department of Pathology
Denver, Colorado 80262

Dr. Leonard Evans
University of California
Department of Molecular Biology
Berkeley, California 94720

Dr. Hidesaburo Hanafusa
The Rockefeller University
New York, New York 10021

Dr. Gilbert Jay
Laboratory of Molecular Virology
National Cancer Institute
National Institutes of Health
Bethesda, Maryland 20205

Dr. Michael Lai
Department of Microbiology
University of Southern California School of Medicine
2011 Zonal Avenue
Los Angeles, California 90033


Japan

Dr. Yoji Ikawa, Chief
Department of Viral Oncology
Cancer Institute
Kami-Ikebukuro, Toshima-ku Tokyo 170, Japan

Dr. Sadaaki Kawai
Associate Professor
Department of Oncostatics
Institute of Medical Science
University of Tokyo
Shiba-Shiroganedai, Minato-ku
Tokyo 108, Japan

Dr. Kin-ichiro Oda
Associate Professor
Department of Cancer Virus
Institute of Medical Science
University of Tokyo
Shiba-Shiroganedai, Minato-ku
Tokyo 108, Japan

Dr. Kumao Toyoshima, Professor
Department of Viral Oncology
Institute of Microbial Diseases
Osaka University
Yamada-ue, Suita-shi
Osaka 565, Japan

Dr. Nobuo Tsuchida
Wistar Institute
36th Street and Spruce
Philadelphia, Pennsylvania 19104

Dr. Ichiro Yahara, Head
Cell Cycle Section
Tokyo Metropolitan Institute of Medical Science
Honkomagome, Bunkyo-ku
Tokyo 113, Japan

Dr. Mitsuaki Yoshida
Chief Associate
Department of Viral Oncology
Cancer Institute
Kami-Ikebukuro, Toshima-ku
Tokyo 170, Japan

Dr. Hiroshi Yoshikura
Associate Professor
Department of Genetics
Institute of Medical Science
University of Tokyo
Shiba-Shiroganedai, Minato-ku
Tokyo 108, Japan



2) Joint Seminar on “Mechanisms of Host Tumor Immunity and Theoretical Basis for Tumor Immunotherapy”
Lahaina Room at the Sheraton-Maui Hotel, October 8-10, 1979

AGENDA

Monday, October 8
(1) ANTIGENIC NATURE OF TUMOR CELLS
Characterization of tumor-associated antigens
8:30-9:10 “Serologic analysis of human osteosarcoma antigens” Dr. S. Rosenberg (National Cancer Institute)
9:10-9:50 “Antigen-characteristics of rat bladder cancer and its relevance to immunosensitivity in immunotherapy” Dr. Y. Hashimoto (Tohoku Univ. Sch. of Pharmacology)
9:50-10:15 “Definition of immune cell surface antigen associated with leukemia” Dr. D. Meruelo (New York University Medical Center)
(2) FUNDAMENTAL IMMUNOLOGIC PROCESS IN HOST RESPONSES TO TUMORS
(a) Mechanisms of macrophage activation and anti-tumor effects
10:30-10:15 “Mode of activation of cytotoxic macrophages” Dr. T. Tokunaga, (National Institute of Health)
11:15-12:00 “Correlation between H2O2 release and the ability of macrophages to kill intracellular protozoa and extracellular tumor cells” Dr. C. Nathan (Rockefeller University)
(b) Natural killer cell activity and relevance to tumor-resistance
20:00-20:45 “Surface marker of mouse natural killer cell” Dr. K. Okumura (Tokyo Univ. Med. Sch.)
20:45-21:30 “Regulation of natural killer cell activity an evidence for role in vivo” Dr. R. Herberman (National Cancer Institute)


Tuesday, October 9
(c) Regulation of host immune response
8:30-9:15 “Regulation of immunity to UV-radiation-induced skin cancer” Dr. M. Kripke (Frederick Cancer Research Center)
9:15-10:00 “Two effector mechanisms against syngeneic tumor in the mouse” Dr. S. Fujimoto (Chiba Univ. Med. Sch.)
10:30-11:15 “The cellular basis of the regulation of the immune response to tumor antigen” Dr. M. Greene (Harvard Medical School)
11:15-12:00 “H-2D linked mechanism of resistance to radiation leukemia virus” Dr. D. Meruelo (New York University Medical Center)
(3) NEW APPROACHES AND PRECLINICAL TRIALS IN TUMOR IMMUNOTHERAPY
20:00-20:45 “Lectin-bound murine tumor cell vaccine: Its immunogeneic and immunotherapeutic potency enhanced by immunomodulators” Dr. T. Kataoka (Japanese Foundation for Cancer Research)
20:45-21:30 “Antitumor activity of quinonyl-N-acetyl-muramyldipeptide derivations” Dr. I. Azuma (Hokkaido Univ. Res. Inst. for Immunol.)

Wednesday, October 10
8:30-9:15 “The prolonged growth of cytotoxic T lymphoid cells” Dr. S. Rosenberg (National Cancer Institute)
9:15-10:00 “Application of T-T cell interaction to tumor immunotherapy” Dr. T. Hamaoka (Osaka Univ. Med. Sch.)
10:00 – 10:45 “The augmentation of in vitro and in vivo tumor-specific T cell-mediated immunity by amplifier T lymphocytes” Dr. H. Fujiwara (National Cancer Institute)
(4) OPEN DISCUSSION
11:00-12:30 “Application of basic tumor immunology studies to the development of new approaches to tumor immunotherapy”

Chairman-Dr. W. Terry (National Cancer Institute)
Japanese Program Leader-Dr. T. Hamaoka (Osaka University)
American Program Leader-Dr. R. Hodes (National Cancer Institute)


PARTICIPANTS

United States

Dr. Richard Hodes,
Principal Advisor
Head, Immunotherapy Section
Immunology Branch, DCBD
National Cancer Institute
Bg. 10, Rm. 4B06 Bethesda, MD 20205
301-496-1376

Dr. Hiromi Fuiiwara
Visiting Fellow
Immunology Branch
National Cancer Institute
Bg. 10, Rm. 4B17 Bethesda, MD 20205
301-496-3626

Dr. Mark Green
Assistant Professor
Harvard Medical School
25 Shattuck Boston, MA 02115
617-732-1973

Dr. Ronald Herberman, Chief
Laboratory of Immunodiagnosis
National Cancer Institute
Bg. 10, Rm. 8B11 Bethesda, MD 20205
301-496-1366

Dr. Margaret Kripke
Cancer Biology Program
Frederick Cancer Research Center
Post Office Box B Frederick, MD 21701
301-663-2091

Dr. Carl Nathan
Rockefeller University
1230 York Avenue New York, New York 10021
212-360-1408

Dr. Daniel Meruelo
New York University Medical Center
Department of Pathology Irvinghouse Institute
212-679-3200, Ext. 3329

Dr. Steven Rosenberg
Chief, Surgery Branch National Cancer Institute
Bg. 10, Rm. 10N116 Bethesda, MD 20205
301-496-4164

Dr. William D. Terry
Director, Immunology Program
National Cancer Institute
Bg. 10, Rm. 4B17 Bethesda, MD 20205
301-496-5461

Japan

Dr. Toshiyuki Hamaoka,
Principal Advisor
Professor and Chairman
Department of Oncogenesis Institute for Cancer Research
Osaka University Medical School
1-1-50 Fukushima, Fukushima-ku Osaka 553, JAPAN

Dr. I. Azuma Hokkaido
University Research Institute for Immunology
Kita-ku Kita 15 Nishi 7 Sapporo 060, JAPAN

Dr. Yoshiyuki Hashimoto
Professor, Tohoku University
Pharmaceutical School
Aramaki, Sendai 980, JAPAN

Dr. T. Kataoka
Japanese Foundation for Cancer Research
Tokyo, JAPAN

Dr. K. Okumura
Tokyo University Medical School
Bunkyo-ku, Hongo 7-3-1 Tokyo 113, JAPAN

Dr. Shigeyoshi Fujimoto
Chiba University
Inohana-cho 1-8-1 Chiba 280, JAPAN

Dr. Toru Tokunaga, Chief
National Institute of Health
Shinagawa-ku Tokyo 141, JAPAN




3) Cytology Automation Meeting
Sheraton Universal Hotel, Los Angeles, CA January 27-29, 1980

AGENDA
Sunday, January 27, 1980
Welcoming Address and Introductions Dr. M. Melamed Dr. Y. Tenjin
An Objective Measure of “How Good” is Cytology Automation Dr. L. Kamensky
Comparison of Data Analysis in Flow and Imaging Systems Dr. T. Sharpless
Multidimensional Slit-Scan Flow System and Correlation Studies Dr. L. Wheeless
An Automatic Detection System of Cancer Cells Based on Multispectral Images Dr. Y. Noguchi
Comparing Human and Machine Performance Dr. J. Prewitt
Monoclonal Antibodies from Human Hybridomas as Specific Immunocytochemical Cell Markers Dr. G. Goldstein


Monday, January 28
Specimen Preparation for Automated Cervical Cancer Cytology Dr. Y. Uei
Improvement of the Preparation Method of Vaginal Smears for Automated Cytology Dr. Y. Kishigami
Detection of Uterine Cancer with an Automated Slide Preparation Technique and High Resolution Scanning in 3 Colors Using the Three-Gun Saticon Camera Dr. G. Wied
Automated Cytological Screening System, Cybest Model 3 and Automated Cell Dispersion and Smearing System Dr. N. Tanaka
Cost and Performance of Cervical Cancer Prescreening Systems Dr. K. Castleman
Cytoanalysis by a new system using an Image Sensor Dr. M. Takahashi
A Study on the Evaluation of the Possibility of Using Flow Cytometry in the First Screening by Automated Cytology Dr. Y. Tenjin
Regulation of the Cell Cycle by Steroid Hormones in HELA Cells: Flow Cytometric Analysis Dr. I. Nishiya
Recognition of Adenocarcinoma in Automated Uterine Cytology Dr. M. Onoe
Flow Cytometry Diagnosis of Carcinoma of the Urinary Bladder Dr. M. Melamed


Tuesday, January 29
Use of Cytometry for Classification of Leukocytes and Leukemias with the Technicon Hemalog D Dr. L. Ornstein
Leukemia Classification and Treatment Monitoring by Flow Cytometry Dr. M. Andreeff
An Overview of the Los Alamos Scientific Laboratory Program in Flow Cytometry Dr. P. Mullaney
An Overview of the Analytic Cytology Program in the Biomedical Sciences Division of the Lawrence Livermore Laboratories Dr. M. Mendelsohn


PARTICIPANTS

United States

Michael Andreeff, M.D., Ph.D.
Memorial Sloan-Kettering Cancer Center
1275 York Avenue New York, NY 10021

Kenneth Castleman, Ph.D.
Jet Propulsion Laboratories California Institute of Technology
Pasadena, CA 91103

Gideon Goldstein, MD., Ph.D.
Ortho Pharmaceutical Corp.
Raritan, NJ 08869

Louis Kamentsky, Ph.D.
Ortho Instruments
410 University Avenue Westwood, MA 02090

Myron Melamed, M.D.
Memorial Sloan-Kettering Cancer Center
1275 York Avenue New York, NY 10021

Mortimer Mendelsohn, Ph.D.
Lawrence Livermore Laboratory
Livermore, CA 94550

Paul Mullaney, Ph.D.
Los Alamos Scientific Laboratory
Los Alamos, NM 87545

Leonard Ornstein, Ph.D.
Mount Sinai School of Medicine Technicon Instruments Corp.
511 Benedict Avenue Tarrytown, NY 10591

Judith Prewitt, Ph.D.
Division of Computer Research & Technology
National Institutes of Health
Bethesda, MD 20205

Thomas Sharpless, Ph.D.
Investigative Cytology Laboratory
Memorial Sloan-Kettering Cancer Center
New York, NY 10021

Leon Wheeless, Ph.D.
Department of Pathology
University of Rochester Medical Center
601 Elmwood Avenue Rochester, NY 14642

George Wied, M.D.
University of Chicago
5841 Maryland Avenue Chicago, IL 60637


Japan

Yoshihiko Kishigami, Head
Department of Clinical Cytology
Osaka Center for Adult Diseases
Osaka, Japan

Iwao Nishiya
Department of Obstetrics & Gynecology
Hokkaido University
Hokkaido, Japan

Yoshio Noguchi
Information Sciences Division
Electrotechmical Laboratory
Tokyo, Japan

Morio Onoe
Institute of Industrial Science
University of Tokyo
Tokyo, Japan

Noboru Tanaka, Director
Chiba Cancer Center Res. Inst.
Chiba, Japan

Masayoshi Takahashi
Department of Pathology
Gifu University
Gifu, Japan

Yoshio Tenjin
Kyoundo Hospital
Sasaki Institute
Tokyo, Japan

Yoshio Uei
Cytology Section
National Cancer Center
Tokyo, Japan