JAPANESE EXCHANGE SCIENTISTS
April 1, 1976 March 31, 1977
Twenty-two Japanese scientists were supported by the Program to conduct collaborative research in laboratories in the United States during the report period. All or a portion of their visits of two weeks to one year (unless modified) took place within the report period: 2 for long-term visits and 20 for short-term visits.
The names of the scientists, their institutional affiliations, their research subjects, their host scientists, and the duration of their visits are given below. The date mentioned in parentheses is the extension of the visit supported by sources external to the Program.
CHEMICAL CARCINOGENESIS
Shozo Takayama
Cancer Institute, Japanese Foundation for Cancer Research
The hamster embryo in vitro carcinogenesis bioassay.
Host: Roman J. Pienta
Frederick Cancer Research Center
May 16, 1976-June 15, 1976
Minro Watanabe
Research Institute For Tuberculosis,
Leprosy and Cancer, Tohoku University
Purification and properties of benzo(a)pyrene hydroxylase system in tissues, Profile of benzo(a)pyrene metabolites in human blood cells under the high pressure liquid chromatography.
Hosts: Allan H. Conney
Hoffmann-La Roche Research Division
Harry V. Gelboin
National Cancer Institute
May 1, 1976-July 31, 1976
Nobuo Nemoto
Research Member, Department of Experimental Pathology, Cancer Institute, Japanese Foundation for Cancer Research
Detoxification enzyme of the active form of benzo(a) pyrene.
Host: Harry V. Gelboin
National Cancer Institute
February 26, 1977-March 31, 1977
(April 1, 1977-April 17, 1977)
CANCER IMMUNOLOGY
Hidechika Okada
National Cancer Center Research Institute
Immunotherapy of cancer and its fundamental bases: cell membrane in immune reaction; adverse effect at immunotherapy of cancer.
Hosts: Donald L. Morton
University of California, Los Angeles
D. Bernard Amos Duke
University Medical Center
June 7, 1976-August 7, 1976
Tsuyoshi Igarashi
Osaka University Medical School
Immunotherapy of cancer and its fundamental bases: the mechanisms for the induction of cell-mediated immunity to syngeneic tumors in mice and cell-mediated immune responses.
Host: Chou-Chik Ting
National Cancer Institute
October 1, 1976-September 30, 1977
CANCER THERAPY
Yoshio Sakurai
Cancer Chemotherapy Center, Japanese Foundation for Cancer Research
Kiyoji Kimura
National Cancer Center Hospital
Tadashi Kimura
National Medical Center Hospital
Makoto Ogawa
Aichi Cancer Center Hospital
Gastrointestinal tumor study group, Boston, Massachusetts.
Hosts: Steve K. Carter
Northern California Cancer Program
Philip S. Schein
Georgetown University School of Medicine
Edward D. Holyoke
State University of New York at Buffalo
Charles G. Moertel
Mayo Medical School, University of Minnesota
Bayard Clarkson Sloan-Kettering Cancer Center
July 10, 1976-July 25, 1976
ANALYTICAL EPIDEMIOLOGY
Minako Nagao
National Cancer Center Research Institute Isolation and characterization of compounds responsible for mutagenicity in broiled fish.
Host: Koji Nakanishi
Columbia University
March 14, 1977-April 13, 1977
BREAST CANCER
Toshio Wagai
Juntendo University School of Medicine
Ultrasonic diagnosis and examination of the breast.
Hosts: William Pomerance
National Cancer Institute
James Greenleaf
Mayo Clinic
James Youker
Medical College of Wisconsin
Kenneth Taylor
Yale University
Barry Goldberg
Episcopal Hospital, Philadelphia
October 10, 1976-October 28, 1976
Yuzuru Kato
Kobe University School of Medicine
Hormone receptor of breast cancer.
Host: William L. McGuire
University of Texas, Health Science Center
January 9, 1977-March 6, 1977
LUNG CANCER
Masatoshi Ichiba
Tokyo Medical College
Immunotherapy, chemotherapy, and surgery of lung cancer; pulmonary and bronchial cytology.
Hosts: John R. Benfield
Harbor General Hospital
Geno Saccomanno
St. Mary's Hospital, Colorado
Edward J. Beattie
Memorial Hospital
Oleg S. Selawry
Comprehensive Cancer Center, Florida
George A. Higgins
Veterans Administration Hospital, Washington
David R. Sanderson
Mayo Clinic, Rochester
Donald L. Paulson
Baylor Medical Plaza
November 1, 1976-December 22, 1976
URINARY BLADDER CANCER
Masataka Mochizuki
Tokyo Biochemical Research Institute
Chemical and biochemical study of carcinogenic nitrosourea compounds; collaboration on the synthesis of C14 labeled nitrosamines for study of their interaction with nucleic acids and nucleosides.
Host: Charles C. Irving
Veterans Administration Hospital, Memphis
September 1, 1976-November 20, 1976
HIGH LET RADIATION THERAPY
Akira Tsuya
Cancer Institute Hospital, Japanese Foundation for Cancer Research
Sadayoshi Fukumoto
National Laboratory for High Energy Physics
Tetsuo Inada
National Institute of Radiological Sciences
Muneyasu Urano
National Institute of Radiological Sciences
High LET radiation therapy.
Hosts: Glenn E. Sheline
University of California, San Francisco
Cornelius Tobias
University of California, Berkeley
Morton Kligerman
Los Alamos Scientific Laboratory
Herman Suit
Massachusetts General Hospital
Henry Kaplan
Stanford University
September 12, 1976-September 26, 1976
Hiroshi Tsunemoto
National Institute of Radiological Sciences
Fast neutron therapy: clinical trial.
Hosts: Gilbert H. Fletcher
M.D. Anderson Hospital, University of Texas
Robert G. Parker
University of Washington, Seattle
Frank H. Attix
Naval Research Laboratory
Charles C. Rogers
The George Washington University
June 21, 1976-September 21, 1976
Akira Ito
Institute of Medical Science, University of Tokyo
Neutron dosimetry; computerized image processing; radiation physics.
Hosts: Peter R. Almond
M.D. Anderson Hospital, University of Texas
Peter Wootton
University of Washington, Seattle
Frank H. Attix
Naval Research Laboratory
January 10, 1977-March 31, 1977
CYTOLOGY
Tadashi Sugishita
Kyoundou Hospital, Sasaki Institute
Comparison of flow analytic/sorting systems with static slide-based image processing system for clinical diagnostic applications.
Host: Paul F. Mullaney
Los Alamos Scientific Laboratory
July 24, 1976-0ctober 4, 1976
METASTASIS
Noritaka Kimura
Faculty of Medicine, Kyushu University
Fundamental approaches to the mechanism of metastasis formation; metastasis and its modification by mucopolysaccharides.
Host: Joseph Leighton
Medical College of Pennsylvania
November 1, 1976-May 31, 1977
JAPANESE EXCHANGE SCIENTISTS
April 1, 1977 March 31, 1978
Twelve Japanese scientists were supported by the Program to conduct collaborative research in laboratories in the United States during the report period. All or a portion of their visits of two weeks to one year (unless modified) took place within the report period: three for long-term visits and nine for short-term visits. The names of the scientists, their institutional affiliations, their research subjects, the host scientists, and the duration of their visits are given below. The date mentioned in parentheses is the extension of the visit supported by sources external to the Program.
CHEMICAL CARCINOGENESIS
Yutaka Tsukada
Associate Professor, Hokkaido University School of Medicine, Department of Biochemistry
Induction of AFP synthesis and secretion by H35 hepatoma cells in serum-free medium by dexamethasone, the interference in this process by insulin, and the effect of delaying the insulin addition while prolonging the Dex treatment: insulin antagonism in a high producer of AFP.
Host: Van Potter
Professor of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin
August 22, 1977-December 2, 1977
Kotaro Koyama
Head, Section of Serology, Serology Division, National Cancer Center Research Institute
Tissue culture of tumor cells: cytoplasmic connection between surface membrane glycoprotein and action-like cytomotile protein.
Host: Senichiro Hakomori
Fred Hutchinson Cancer Research Center and University of Washington
September 1, 1977-February 28, 1978 (March 1, 1978-August 29, 1978)
CANCER VIROLOGY
Akiia Seto
Associate Professor, Faculty of Medicine, Kyoto University
Studies on the immune reactions against virus-induced tumors and the activation of endogenous type C viruses.
Hosts: Gary Pearson
Mayo Clinic
John Moloney
National Cancer Institute
Ronald Herberman
National Cancer Institute
September 1, 1977-November 30, 1977 (December 1, 1977-December 28, 1977)
CANCER IMMUNOLOGY
Takashi Mori
Chief, Department of Surgery, National Kinki Chuo Hospital
Immunotherapy of cancer.
Hosts: Hiroshi Takita
Roswell Park Memorial Institute
William D. Terry
National Cancer Institute
Herbert Oettgen
Memorial Sloan-Kettering Cancer Center
Martin McKneally
Albany Medical College
Michael Mastrangelo
American Oncologic Hospital
Evan Hersh
M.D. Anderson Hospital, University of Texas
Carmack Holmes
University of California, Los Angeles
September 15, 1977-December 14, 1977
Kosei Yasumoto
Staff, Department of Chest Surgery National Kyushu Cancer
Center Immunology and immunotherapy.
Hosts: Hiroshi Takita
Roswell Park Memorial Institute
Martin McKneally
Albany Medical College
William D. Terry
National Cancer Institute
Carmack Holmes
University of California, Los Angeles
March 1, 1978-March 31, 1978
CANCER THERAPY
Masaaki Ishizuka
Senior Researcher, Institute of Microbial Chemistry
Cancer chemotherapy and immunotherapy of cancer by microbial products.
Hosts: John D. Douros
National Cancer Institute
A. Langlykke
Frederick Cancer Research Center
V. Riley
Pacific Northwest Research Foundation
E.A. Boyse
Memorial Sloan-Kettering Cancer Center
B. Bonavida
University of California, Los Angeles
D.R. Webb
Roche Institute of Molecular Biology
June 16, 1977-July 10, 1977
ANALYTICAL EPIDEMIOLOGY
Suketami Tominaga
Chief, Division of Epidemiology, Aichi Cancer Center Research Institute
Study of the recent trends in epidemiological carcinogenesis in the U. S.
Host: Abraham Lilienfeld
Johns Hopkins University
September 1, 1977-September 30, 1977
BREAST CANCER
Goi Sakamoto
Assistant Pathologist, Cancer Institute Japanese Foundation for Cancer Research
Clinico-pathological study on breast cancer.
Host: William Hartmann
Professor, Vanderbilt University School of Medicine
September 15, 1977-March 9, 1978
LUNG CANCER
Nagahiro Saijo
Medical Staff of Internal Medicine, National Cancer Center Hospital
Tumor immunology and immunochemotherapy of experimental tumors.
Host: Evan M. Hersh
M.D. Anderson Hospital, University of Texas
September 1, 1977-February 28, 1978 (March 1, 1978-June 30, 1978)
URINARY BLADDER CANCER
Yoshiyuki Ohno
Assistant, Department of Preventive Medicine, Nagoya University School of Medicine
Epidemiology of bladder cancer.
Hosts: Allan Morrison
Harvard University School of Public Health
George Bryan
University of Wisconsin
September 10, 1977-November 9, 1977
HIGH LET RADIATION THERAPY
Yu lino
Associate Professor, Institute of Medical Science, University of Tokyo
Fast neutron radiation therapy.
Host: David H. Hussey
M.D. Anderson Hospital, University of Texas
November 27, 1977-December 18, 1977
CYTOLOGY
lwao Nishiya
Associate Professor, Department of Obstetrics and Gynecology, Hokkaido University School of Medicine
Cytochemical investigations on the changes in DNA and histone of premalignant epithelial cells; microspectrophotometry and fiberoptic scanning.
Host: Chester J. Herman
National Cancer Institute
October 1, 1977-January 31, 1978 (February 1, 1978-May 20, 1978)
AMERICAN EXCHANGE SCIENTISTS
April 1976 December 1977
Thirty-one American scientists were supported by the Program to conduct collaborative research in laboratories in Japan during the report period. All or a portion of their visits of two weeks to one year (unless modified) took place within the report period. The names of the scientists, their institutional affiliations, their research subjects, the host scientists, and the duration of their visits are given below.
CHEMICAL CARCINOGENESIS
Abraham Hsie
Oak Ridge National Laboratory, Tennessee
To engage in collaborative research on experimental carcinogenesis at Cancer Institute and National Cancer Center, Tokyo.
Hosts: Takashi Sugimura
T. Matsushima
National Cancer Center Research Institute, Tokyo
June 1-August 1, 1977
Lowell Greenbaum
College of Physicians and Surgeons New York City
Collaborative research and to meet leading Japanese cancer researchers in Tokyo and Fukuoka to discuss recent advances in the area of carcinogenesis.
Host: Yuichi Yamamura
Department of Internal Medicine, Osaka University
June 26-August 28, 1977
Veronica Maher
Michigan State University, East Lansing
To attend meeting and give lectures and seminars on DNA repair and misrepair.
Host: Takashi Sugimura
National Cancer Center Research Institute, Tokyo
December 3-17, 1977
Walter Troll
New York University Medical Center New York City
To attend meeting and give lectures and seminars on DNA repair and misrepair.
Host: Takashi Sugimura
National Cancer Center Research Institute, Tokyo
December 3-17, 1977
I. Bernard Weinstein
Institute for Cancer Research Columbia University
To attend meeting and give lectures and seminars on DNA repair and misrepair.
Host: Takashi Sugimura
National Cancer Center Research Institute, Tokyo
December 3-17, 1977
CANCER VIROLOGY
Richard Junghans
California Institute of Technology Pasadena, California
Gave course on heteroduplex technique and engaged in collaborative research to map the site of the deletion in a TD-ASV mutant which was isolated.
Host: Yoji Ikawa
Cancer Institute, Japanese Foundation for Cancer Research
September 3-23, 1977
Kenneth Takemoto
National Cancer Institute, NIH
To give lectures and seminars at several institutions in Japan on the subject “New Human Papovaviruses.”
Host: Yohei Ito
Kyoto University, Kyoto
October 3-14, 1977
CANCER IMMUNOLOGY
Charles W. Boone
National Cancer Institute, NIH
Engaged in collaborative research on tumor immunology in laboratory of Dr. H. Kobayashi to explore mechanisms and applications of the phenomenon of the “virus-augmentation” of tumorigenecity.
Host: H. Kobayashi
University of Hokkaido, Sapporo
September 4, 1976-0ctober 14, 1976
William D. Terry
National Cancer Institute
Hosts: Yuichi Yamamura
Osaka University
Tadashi Yamamoto
Institute of Medical Science University of Tokyo
Tomio Tada
Chiba University
Hiroshi Kobayashi
Hokkaido University
September 25, 1976-0ctober 15, 1976
BREAST CANCER
William Hartmann
Vanderbilt University, Tennessee
Lectures on breast cancer screening and the relationship of fibrocystic disease and breast cancer. Also spent time in Dr. Sugano’s laboratory at the Cancer Institute, the National Cancer Center, Tohoku University, and Kyoto University.
Host: Haruo Sugano
National Cancer Center Research Institute, Tokyo
June 23, 1976-August 1, 1976
URINARY BLADDER CANCER
George T. Bryan
University of Wisconsin, Madison
To assess the Bladder Cancer Program with counterpart Program Coordinator and make future plans.
Host: Osamu Yoshida
University of Kyoto, Kyoto
April 16-30, 1977
Samuel M. Cohen
St. Vincents Hospital, Massachusetts
Collaborative research activities in bladder cancer.
Host: Nobuyuki Ito
Nagoya City Medical School, Nagoya
July 5, 1976-June 4, 1977
HIGH LET RADIATION THERAPY
Peter Almond
M.D. Anderson Hospital, Houston, Texas
Hans Bischel
University of Washington, Seattle
James Smathers
Texas A&M University, College Station
Engage in collaborative research with physicists and other radiation specialists at the Institute of Medical Research in Tokyo and the National Institute of Radiological Sciences in Chiba City. Research on physical dosimetry measurements on neutron generators.
Host: Tadashi Hashizume
National Institute of Radiological Sciences, Chiba
April 12-20, 1976
TWO-MAN TEAMS-THREE-WEEK VISITS:
Eric Hall
Radiological Research Laboratories College of Physicians and Surgeons, New York
H. Rodney Withers
M.D. Anderson Hospital, Houston
Host: Keisuke Misuno
National Institute of Radiological Sciences, Chiba
December 5-15, 1976
Raymond Meyn
M.D. Anderson Hospital, Houston, Texas
Janet Nelson Racey
University of Washington, Seattle
Host: Keisuke Misuno
National Institute of Radiological Sciences, Chiba
January 22, 1977-February 4, 1977
Joseph Geraci
University of Washington, Seattle
Paul Todd
Pennsylvania State University
To collaborate on comparative studies on biological effects and dosimetry of high energy particles.
Host: Keisuke Misuno
National Institute of Radiological Sciences, Chiba March 5-20, 1977
Herman Suit
Massachusetts General Hospital, Boston
Peter Almond
University of Texas System Cancer Center, Houston
To discuss high radiation with the staff at the institute of Medical Sciences and the National Institute of Radiological Sciences and attend seminars and visit other laboratories.
Host: Akira Tsuya
Cancer Institute, Japanese Foundation for Cancer Research, Tokyo
September 18, 1977-0ctober 2, 1977
Hermann A. Grunder
Lawrence Berkeley Laboratory, California
To discuss high radiation with the staff at the Institute of Medical Science and the National Institute of Radiological Sciences and attend seminars and visit other laboratories.
Host: Akira Tsuya
Cancer Institute, Japanese Foundation for Cancer Research, Tokyo
September 18, 1977-0ctober 9, 1977
Theodore Phillips
University of California, San Francisco
To discuss high radiation with the staff at the Institute of Medical Science and the National Institute of Radiological Sciences and attend seminars and visit other laboratories.
Host: Akira Tsuya
Cancer Institute, Japanese Foundation for Cancer Research, Tokyo
September 19, 1977-0ctober 2, 1977
METASTASIS
Isaiah Fidler
Frederick Cancer Research Center, Frederick, Maryland
George Poste
Roswell Park Memorial Institute, Buffalo, New York
Visited eight academic centers working on various aspects of metastasis and at each center presented a seminar on “The Biology of Metastasis.” Also spent time discussing ongoing research in their laboratories as well as their host’s laboratories.
Host: Haruo Sato
Tohoku University, Sendai
May 29, 1977-June 15, 1977
CYTOLOGY
T. Sharpless
Memorial Hospital for Cancer and Allied Diseases
Myron Melamed
Memorial Hospital for Cancer and Allied Diseases
Paul Mullaney
Los Alamos Scientific Laboratory
Leon Wheeless
University of Rochester
For lecture-demonstrations on analytical cytology including sample preparative and cell analytic techniques.
Host: Kiyoji Kimura
National Cancer Center Hospital
April 27, 1977-May 10, 1977